INTRACRANIAL RING ENHANCING LESIONS IN DOGS: A CORRELATIVE CT SCANNING AND NEUROPATHOLOGIC STUDY     

Michael  Wolf  Dr. Vet. Med.  Vince  Pedroia  DVM  Robert J.  Higgins  BVSc  PhD  Philip D.  Koblik  DVM  MS  Jane M.  Turrel  DVM  MS  Jerry M.  Owens  DVM 《Veterinary radiology & ultrasound》1995,36(1):16-20

This retrospective analysis of 15 dogs with postcontrast ring enhancing brain lesions, each detected by a single Computed Tomography [CT] examination, searched for any association between their CT appearance and the pathologic diagnosis. In a subgroup of these dogs [n = 7] necropsied within 2 days of the last CT scan, we evaluated whether there was any anatomic correlation between the ring zone and the histopathologic features of the lesions. Our study consisted of eight dogs with primary brain tumors [3 meningiomas, 3 astrocytomas, 1 mixed glioma, 1 oligodendroglioma], 4 with metastatic brain tumors [2 fibrosarcomas, 1 mammary carcinoma, 1 melanoma] and 3 with non-neoplastic brain lesions [2 intraparenchymal hemorrhages, 1 pyogranulomatous meningoencephalitis]. The overall size and shape of the contrast enhancing CT lesions, as well as the thickness, surface texture and degree of enhancement of the ring were subjectively evaluated. No association was found between the CT lesion characteristics and the pathologic diagnosis. In the sub-group of dogs euthanatized within 2 days of the CT examination, distinct histologic features which anatomically correlated with the zone of ring enhancement were found in 3 of 7 lesions. The findings of this study are consistent with those of ring-enhancing lesions in people, and indicates that CT ring enhancement is a non-specific phenomenon which can occur in a variety of neoplastic and non-neoplastic lesions in the dog.  相似文献   

Central nervous system lymphosarcoma in the dog   总被引：1，自引：0，他引：1  

C G Couto  J Cullen  V Pedroia  J M Turrel 《Journal of the American Veterinary Medical Association》1984,184(7):809-813

Central nervous system lymphosarcoma was diagnosed in 8 dogs with seizures and clinical signs compatible with multifocal central nervous system involvement. Cerebrospinal fluid analysis showed high white cell counts with abnormal lymphoid cells in all dogs, and high protein concentration in 5 dogs. Two dogs were given systemic anticancer chemotherapy, and 4 dogs were given a combination of systemic chemotherapy, intrathecal cytosine arabinoside, and craniospinal irradiation, resulting in marked improvement of the clinical signs.  相似文献   

MAGNETIC RESONANCE IMAGING AND COMPUTED TOMOGRAPHY CHARACTERISTICS OF INTRACRANIAL INTRA-ARACHNOID CYSTS IN 6 DOGS   总被引：2，自引：0，他引：2  

Karen M.  Vernau  DVM  Gregg D.  Kortz  DVM  Philip D.  Koblik  DVM  MS  Richard A.  Lecouteur  BVSc  PhD  Cleta Sue  Bailey  DVM  PhD  Vince  Pedroia  DVM 《Veterinary radiology & ultrasound》1997,38(3):171-176

Magnetic resonance imaging (MRI) and computed tomographic imaging (CT) characteristics of intracranial intra-arachnoid cysts in six dogs are described.Of the six dogs, three were less than one year of age and 4 were males. Five of the six dogs weighed less than 11 kg. Five cysts were located in the quadrigeminal cistern.On CT images, the intracranial intra-arachnoid cysts had sharply defined margins, contained fluid isodense to CSf and did not enhance following IV administration of contrast. On MRI images, the intracranial intra-arachnoid cysts were extra-axial, contained fluid isointense with CSF and did not enhance following IV contrast. While spinal arachnoid cysts of dogs have been reported in the literature, other than the six dogs contained in this report, intracranial intra-arachnoid cysts have not to our knowledge been described in animals. These six dogs have a similar age, sex, arachnoid cysts.  相似文献   

COMPUTED TOMOGRAPHY OF BRAIN TUMORS IN THE CAUDAL FOSSA OF THE DOG*     

RichardA. LeCouteur  JohnR. Fike  ChristopherE. Cann  VincentG. Pedroia 《Veterinary radiology & ultrasound》1981,22(6):244-251

Computed tomography (CT) was used to investigate brain tumors in the caudal fossa of three dogs. Changes detected by CT included compression or distortion of cerebrospinal fluid spaces within the caudal fossa, and changes in parenchymal density before and after intravenous injection of a nondiffusible, iodinated contrast medium. CT provided information regarding tumor size, location, character, and relationships with normal caudal fossa structures. It was concluded that CT offered advantages over technics currently in use for diagnosis and assessment of caudal fossa lesions in the dog.  相似文献