Levels of selenium in blood and tissues associated with some selenium deficiency diseases in New Zealand sheep     

Sheppard AD  Blom L  Grant AB 《New Zealand veterinary journal》1984,32(6):91-95

Whole bloods from weaned lambs with severe selenium responsive unthriftiness usually contain <5 ng Se/ml. Mildly or moderately affected lambs have blood levels of 5-10 ng/ml. Selenium responsive infertility in ewes appears to be associated with whole blood selenium levels below 10 ng/ml.  相似文献   

Failure of orally administered zinc to prevent experimentally induced footrot in sheep     

Skerman TM  Millar KR  Sheppard AD  Herceg M  Hughes JM 《New Zealand veterinary journal》1983,31(4):54-57

Two groups of adult Merino sheep, initially grazed on pasture, were dosed daily with zinc sulphate (1 mg Zn/kg LW) or zinc oxide (15 mg Zn/kg LW) for six and seven weeks, respectively. On the 18th day, both groups were transferred to indoor pens together with unmedicated control sheep, and five days later the feet of all animals were infected artificially with a virulent strain of Bacteroides nodosus. By the fourth week after challenge, 85% or more of the feet challenged had developed advanced footrot, and no significant differences in the incidence and severity of lesions between dosed and un-dosed groups were recorded. Plasma zinc concentrations, monitored throughout the experiment, remained at similar levels in sheep receiving the lower dose rate and in the controls. At the higher dose rate, plasma zinc levels increased till Day 23, but thereafter declined to values comparable to those of undosed animals. At post mortem, no evidence of zinc toxicosis was found, and only the kidneys of sheep receiving the higher dosage showed a significant accumulation of zinc compared with the controls.  相似文献   

Pericardial lipoma in a geriatric dog with an incidentally discovered thoracic mass     

Ben-Amotz R  Ellison GW  Thompson MS  Sheppard BJ  Estrada AH  Levy JK 《The Journal of small animal practice》2007,48(10):596-599

An intrathoracic mass was discovered as an incidental finding in a 14-year-old, spayed, female Rottweiler cross during evaluation of urinary incontinence. Computed tomography suggested a pericardial or pleural location and high adipose content of the mass. The mass was removed via lateral thoracotomy with partial pericardectomy and was diagnosed as a pericardial lipoma. The dog recovered well, and there was no evidence of recurrence approximately one year later. Adipose tumours of the heart and its associated structures are rare in dogs and have been associated with both successful and fatal outcomes.  相似文献   

Performance,milk fatty acid composition and behaviour of high-yielding Holstein dairy cows given a limited grazing period     

Norton E. Atkins  Claire Cianchi  S. M. Rutter  Sarah J. Williams  Carrie Gauld  Gemma L. Charlton  Liam A. Sinclair 《Grass and Forage Science》2020,75(2):181-191

The effects of a limited grazing period on the performance, behaviour and milk composition of high-yielding dairy cows were examined. A total of 56 Holstein cows yielding 44.7 ± 0.42 kg/day were allocated to one of four treatments in one of two, 4-week periods. Treatments were as follows: control (C)—cows housed and offered TMR ad libitum; early grazing (EG)—cows grazed for 6 hr after morning milking then housed; delayed grazing (DG)—cows returned to housing for 1 hr after morning milking followed by grazing for 6 hr, then housed; restricted TMR (RT)—cows grazed for 6 hr after morning milking, then housed and fed TMR at 75% of ad libitum. Intake of TMR was highest in cows receiving C, intermediate in EG and DG, and lowest in RT at 26.9, 23.6, 24.7 and 20.3 kg DM/day respectively. Pasture intake was similar in cows receiving EG or DG, but was higher in RT at 2.4, 2.0 and 3.5 kg DM/day respectively. Milk yield was similar between cows receiving C, EG or DG, but lowest in RT at 45.7, 44.2, 44.9 and 41.7 kg/cow, respectively, while milk fat content of C18:3 n-3 was increased by grazing. Cows in C spent more than 55 min/day longer lying and had three additional lying bouts/day, while lying bouts were shorter than for cows receiving EG, RT or DG. It is concluded that high-yielding cows can be grazed for 6 hr/day with little impact on performance, provided TMR is available ad libitum when housed.  相似文献   

A high-resolution radiation hybrid map of the human genome draft sequence     

Olivier M  Aggarwal A  Allen J  Almendras AA  Bajorek ES  Beasley EM  Brady SD  Bushard JM  Bustos VI  Chu A  Chung TR  De Witte A  Denys ME  Dominguez R  Fang NY  Foster BD  Freudenberg RW  Hadley D  Hamilton LR  Jeffrey TJ  Kelly L  Lazzeroni L  Levy MR  Lewis SC  Liu X  Lopez FJ  Louie B  Marquis JP  Martinez RA  Matsuura MK  Misherghi NS  Norton JA  Olshen A  Perkins SM  Perou AJ  Piercy C  Piercy M  Qin F  Reif T  Sheppard K  Shokoohi V  Smick GA  Sun WL  Stewart EA  Fernando J  Tejeda  Tran NM  Trejo T  Vo NT  Yan SC  Zierten DL  Zhao S 《Science (New York, N.Y.)》2001,291(5507):1298-1302

We have constructed a physical map of the human genome by using a panel of 90 whole-genome radiation hybrids (the TNG panel) in conjunction with 40,322 sequence-tagged sites (STSs) derived from random genomic sequences as well as expressed sequences. Of 36,678 STSs on the TNG radiation hybrid map, only 3604 (9.8%) were absent from the unassembled draft sequence of the human genome. Of 20,030 STSs ordered on the TNG map as well as the assembled human genome draft sequence and the Celera assembled human genome sequence, 36% of the STSs had a discrepant order between the working draft sequence and the Celera sequence. The TNG map order was identical to one of the two sequence orders in 60% of these discrepant cases.  相似文献   

Compliments on management and behavior study     

Sheppard GA 《Journal of the American Veterinary Medical Association》2000,217(6):818

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NOTE ON THE THEORY OF PHOTOGRAPHIC SENSITIVITY     

Sheppard SE  Wightman EP 《Science (New York, N.Y.)》1923,58(1492):89-91

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Habitat mapping in the Caribbean for management and conservation: Use and assessment of aerial photography     

C. R. C. Sheppard  K. Matheson  J. C. Bythell  P. Murphy  C. Blair Myers  B. Blake 《水产资源保护:海洋与淡水生态系统》1995,5(4):277-298

• 1 The nature and distribution of the coastal and shallow marine habitats of Anguilla in the Caribbean were examined using aerial photography coupled with extensive ground truth information.
• 2 The objective was to develop an accurate method of marine habitat mapping for the analysis of the marine ecosystem in order to develop a procedure for marine and coastal resource management.
• 3 This paper describes the method which was adopted as well as the biological results.
• 4 It is concluded that the management and sustainable use of the natural resources may be improved as a result of accurate habitat mapping.

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Eight urgent,fundamental and simultaneous steps needed to restore ocean health,and the consequences for humanity and the planet of inaction or delay     

Dan Laffoley  John M. Baxter  Diva J. Amon  Duncan E.J. Currie  Craig A. Downs  Jason M. Hall‐Spencer  Harriet Harden‐Davies  Richard Page  Chris P. Reid  Callum M. Roberts  Alex Rogers  Thorsten Thiele  Charles R.C. Sheppard  Rashid U. Sumaila  Lucy C. Woodall 《水产资源保护:海洋与淡水生态系统》2020,30(1):194-208

1. The ocean crisis is urgent and central to human wellbeing and life on Earth; past and current activities are damaging the planet's main life support system for future generations. We are witnessing an increase in ocean heat, disturbance, acidification, bio‐invasions and nutrients, and reducing oxygen levels. Several of these act like ratchets: once detrimental or negative changes have occurred, they may lock in place and may not be reversible, especially at gross ecological and ocean process scales.
2. Each change may represent a loss to humanity of resources, ecosystem function, oxygen production and species. The longer we pursue unsuitable actions, the more we close the path to recovery and better ocean health and greater benefits for humanity in the future.
3. We stand at a critical juncture and have identified eight priority issues that need to be addressed in unison to help avert a potential ecological disaster in the global ocean. They form a purposely ambitious agenda for global governance and are aimed at informing decision‐makers at a high level. They should also be of interest to the general public.
4. Of all the themes, the highest priority is to rigorously address global warming and limit surface temperature rise to 1.5°C by 2100, as warming is the pre‐eminent factor driving change in the ocean. The other themes are establishing a robust and comprehensive High Seas Treaty, enforcing existing standards for Marine Protected Areas and expanding their coverage, especially in terms of high levels of protection, adopting a precautionary pause on deep‐sea mining, ending overfishing and destructive fishing practices, radically reducing marine pollution, putting in place a financing mechanism for ocean management and protection, and lastly, scaling up science/data gathering and facilitating data sharing.
5. By implementing all eight measures in unison, as a coordinated strategy, we can build resilience to climate change, help sustain fisheries productivity, particularly for low‐income countries dependent on fisheries, protect coasts (e.g. via soft‐engineering/habitat‐based approaches), promote mitigation (e.g. carbon storage) and enable improved adaptation to rapid global change.

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Cell-surface changes after infection with oncogenic viruses: requirement for synthesis of host DNA   总被引：2，自引：0，他引：2  

J R Sheppard  A J Levine  M M Burger 《Science (New York, N.Y.)》1971,172(990):1345-1346

The change in the surface structure of cultutred mammalian cells infected with oncogenic DNA viruses was similar to that described for the fully and permanently transformed cell surfaces. The course of appearance of this change was established. Synthesis of host DNA is required for expression of the surface change triggered by infection with the oncogenic virus.  相似文献