Ovine hereditary chondrodysplasia (spider syndrome) in Suffolk lambs   总被引：1，自引：0，他引：1  

PH PHILLIPS  CM BUNN  CE ANDERSON 《Australian veterinary journal》1993,70(2):73-74

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FC-17 Cutaneous papillomatosis and carcinomatosis in the highly endangered Western Barred Bandicoot   总被引：1，自引：0，他引：1  

A. J.O''hara  K. S.Warren  R. A.Swan  C.Simms  J. A.Friend 《Veterinary dermatology》2004,15(S1):25-25

Newcastle disease virus (NDV) has antineoplastic and immunostimulatory properties, and it is currently being clinically tested in anticancer therapy. In order to analyse the immunostimulatory effects of NDV on bovine papillomatosis, we inoculated 14 cows subcutaneously with an attenuated vaccine containing the LaSota strain of NDV (LS-NDV). Four cows with papillomatosis served as controls. Serum samples were collected from each animal 1 h preinoculation and 7 and 21 days postinoculation. In inoculated cows on days 7 and 21, the mean antibody titres were log₂ 2.43 ± 0.92 and 5.57 ± 0.72, respectively, by haemagglutination inhibition, and the mean levels of TNFα were 5.80 ± 4.19 and 5.39 ± 2.66 ng/mL, respectively, by WEHI-164 cytotoxicity assay. Significant differences between inoculated and control animals were evident for antibody titres on day 21 and clinical scores on day 60. A correlation was evident between the TNFα activities and clinical scores on day 21. The clinical observations at day 60 showed that the papillomas in five cows had completely resolved (36%), one animal had no alterations on clinical appearance of the tumour (7%), and papillomas in eight cows had regressed (57%). In conclusion, these results demonstrated that inoculation of LS-NDV vaccine stimulates an antibody response and a limited increase in TNFα activity and may enhance clinical recovery in bovine papillomatosis.
Funding: Scientific Research Council of Akdeniz University.  相似文献   

Outcome of reconstruction of cutaneous limb defects in dogs using hygroscopic “self‐inflating” tissue expanders          下载免费PDF全文

M. De Lorenzi  M. C. Swan  C. Easter  G. P. A. Chanoit 《The Journal of small animal practice》2018,59(2):98-105

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The toxic effect of massive doses of calciferol on dairy cows     

J.B. Swan B.V.Sc. 《New Zealand veterinary journal》2013,61(2):25-27

Extract

Evidence that feeding massive doses, of calciferol prior to calving may be a useful method of preventing milk fever was obtained by Hibbs and co-workers (1950, 1951) at Ohio State University. The treatment causes a rise in serum calcium and if dosing is suitably timed the post-partum fall in serum calcium may be countered, thus making up for the presumed parathyroid failure which occurs at this lime and which is believed by many to be the underlying cause of milk fever.  相似文献   

Relative bioavailability of rafoxanide following intraruminal and intra-abomasal administration in sheep     

Swan GE  Koeleman HA  Steyn HS  Mülders MS 《Journal of the South African Veterinary Association》1999,70(2):71-74

The bioavailability of rafoxanide was compared after intraruminal and intra-abomasal administration in healthy adult sheep (n = 6) in a single dose, 2 parallel group study at 7.5 mg/kg. Rafoxanide concentrations in plasma were measured by means of HPLC analysis. Primary pharmacokinetic parameters for bioavailability and disposition of rafoxanide in plasma for both routes of administration were determined by non-compartmental and non-linear, 1-compartmental pharmacokinetic analysis, respectively. Significantly (P < or = 0.05) higher peak plasma concentrations (c(max)) of rafoxanide and a more rapid rate of absorption (c. 3.5 times) was observed in sheep after intra-abomasal (i-a) administration compared to intraruminal (i.r.) administration. A significantly (P < or = 0.05) longer lag period (t(lag)) before absorption (6.8 +/- 2.9 h) occurred after i.r. than after i-a treatment (1.9 +/- 0.6 h). There was no significant difference (P > 0.05) in AUC, MRT and in the rates of elimination (k10-HL and t(1/2beta)) between the i.r. and i-a routes of administration. The results of the study demonstrated the important influence of the rumino-reticulum on absorption of rafoxanide in sheep.  相似文献   

Cryptosporidium muris infection in bilbies (Macrotis lagotis)     

Warren KS  Swan RA  Morgan-Ryan UM  Friend JA  Elliot A 《Australian veterinary journal》2003,81(12):739-741

Cryptosporidiosis is an enteric disease of animals and humans that can be fatal in immunocompromised individuals. There is no known effective treatment for cryptosporidiosis. Bilbies are threatened marsupials and are bred in captivity as part of a recovery program to re-introduce this species to the southwest of Western Australia. Cryptosporidium muris infection was detected in the faeces of bilbies at a captive breeding colony. Stress associated with a high density of bilbies in enclosures may have predisposed some of the bilbies to infection with C. muris. C. muris has been described in mice and was found in the faeces of one mouse trapped in the breeding enclosures. It is likely the bilbies acquired the infection from mice by faecal contamination of food and water. The infection cleared within 2 months from some bilbies, however others remained infected for 6 months and treatment was attempted with dimetridazole. Subsequently the parasite was no longer be detectable in the faeces.  相似文献   

Screening of five drugs for efficacy against Babesia felis in experimentally infected cats     

Penzhorn BL  Lewis BD  López-Rebollar LM  Swan GE 《Journal of the South African Veterinary Association》2000,71(1):53-57

The efficacy of 5 drugs was tested against experimental Babesia felis infection in domestic cats. Two of the drugs, rifampicin and a sulphadiazine-trimethoprim combination, appeared to have an anti-parasitic effect, but were inferior to primaquine. The other 3 drugs, buparvaquone, enrofloxacin and danofloxacin, had no significant anti-babesial effect.  相似文献   

Successful medical treatment of splenic abscesses in a horse     

CM STEEL  RA LONSDALE  JR BOLTON 《Australian veterinary journal》1998,76(8):541-542

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Control of perineal squamous cell carcinoma in ewes     

R A Swan  C D Hawkins  H M Chapman 《Australian veterinary journal》1985,62(S1):143-143

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T-shaped malformation of the ventral colon in a Thoroughbred filly with colic     

GD Trope  CM Steel 《Australian veterinary journal》2010,88(8):322-325

A 4-month-old Thoroughbred filly presented for abdominal pain was diagnosed with a T-shaped malformation of the ventral colon at exploratory laparotomy. Following resection and anastomosis of the large colon, no further episodes of abdominal pain occurred during a 12-month follow-up. Acute dehiscence of the linea alba occurred as a complication of the initial laparotomy, but was successfully managed following additional surgical repair. T-shaped malformation of the ventral colon has not previously been reported and is considered a congenital malformation of mesocolon formation.  相似文献