Successful treatment of a horse with chronic, severe flexural deformity of the distal interphalangeal joint: A case report     

Stacey Tarr DVM  Doug Butler PhD  CJF  FWCF  Robert K. Shideler DVM  ACT 《Journal of Equine Veterinary Science》1993,13(12):711-714

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Investigation of Interspecies Interactions within Marine Micromonosporaceae Using an Improved Co-Culture Approach     

Navid Adnani  Emmanuel Vazquez-Rivera  Srikar N. Adibhatla  Gregory A. Ellis  Doug R. Braun  Tim S. Bugni 《Marine drugs》2015,13(10):6082-6098

With respect to bacterial natural products, a significant outcome of the genomic era was that the biosynthetic potential in many microorganisms surpassed the number of compounds isolated under standard laboratory growth conditions, particularly among certain members in the phylum Actinobacteria. Our group, as well as others, investigated interspecies interactions, via co-culture, as a technique to coax bacteria to produce novel natural products. While co-culture provides new opportunities, challenges exist and questions surrounding these methods remain unanswered. In marine bacteria, for example, how prevalent are interspecies interactions and how commonly do interactions result in novel natural products? In an attempt to begin to answer basic questions surrounding co-culture of marine microorganisms, we have tested both antibiotic activity-based and LC/MS-based methods to evaluate Micromonosporaceae secondary metabolite production in co-culture. Overall, our investigation of 65 Micromonosporaceae led to the identification of 12 Micromonosporaceae across three genera that produced unique metabolites in co-culture. Our results suggest that interspecies interactions were prevalent between marine Micromonosporaceae and marine mycolic acid-containing bacteria. Furthermore, our approach highlights a sensitive and rapid method for investigating interspecies interactions in search of novel antibiotics, secondary metabolites, and genes.  相似文献   

Unravelling the impacts of disturbance type and regeneration on movement of threatened species     

Finnegan  Laura  Viejou  Rebecca  MacNearney  Doug  Pigeon  Karine E.  Stenhouse  Gordon B. 《Landscape Ecology》2021,36(9):2619-2635

Landscape Ecology - Anthropogenic disturbance alters animal movements. Large mammals require vast areas to meet their needs, and they encounter anthropogenic disturbances frequently during daily...  相似文献   

The incredible fungal genus —Drechslera — and its phytotoxic ophiobolins     

Gary Strobel  Doug Kenfield  Fumio Sugawara 《Phytoparasitica》1988,16(2):145-152

ManyDrechslera species that haveCochliobolus sp. as a perfect stage produce a related group of ophiobolins, sesterterpenoids (C-25’s), which are phytotoxic to a wide range of plants. One of the most toxic ophiobolins is 6-epiophiobolin A and it is produced by all of theDrechslera species thus far studied. On the other hand, some novel ophiobolins have been found inD. oryzae: ophiobolin J, 6-epiophiobolin I, and 8-deoxyophiobolin J. Potentially, genetic crosses made between these fungi could yield novel organisms, producing novel combinations of the ophiobolins, and thus new pathotypes. Ophiobolins are being used in tissue culture systems to screen plants for sensitivity to these toxins. Paper presented at the Bat-Sheva Seminar on Host - Fungus Interaction, Jerusalem, Israel (March 14–25,1988).  相似文献   

Field evaluation of moxidectin/praziquantel oral gel in horses     

Grubbs ST  Amodie D  Rulli D  Wulster-Radcliffe M  Reinemeyer C  Yazwinski T  Tucker C  Hutchens D  Smith L  Patterson D 《Veterinary therapeutics : research in applied veterinary medicine》2003,4(3):249-256

The safety and efficacy of 2% moxidectin/12.5% praziquantel oral gel administered at a rate of 0.4 mg moxidectin and 2.5 mg praziquantel/kg was studied in client-owned horses under field use conditions. Four hundred horses (300 treated with moxidectin/praziquantel oral gel and 100 treated with vehicle) were enrolled, feces were collected, and eggs were counted. Investigators as well as horse owners were masked to treatment assignment. No adverse reactions to treatment were observed in any horses. Moxidectin/praziquantel gel reduced Anoplocephala spp by more than 99% and provided a significant (P <.05) reduction (> 98%) in the strongyle egg count of treated horses.  相似文献   

Good communication skills key to success          下载免费PDF全文

Hare D 《The Canadian veterinary journal. La revue veterinaire canadienne》2003,44(8):621-622

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Reviewers deserve better recognition          下载免费PDF全文

Hare D 《The Canadian veterinary journal. La revue veterinaire canadienne》2002,43(12):905-906

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Effect of monensin on survival and growth of Escherichia coli O 157:H7 in vitro          下载免费PDF全文

Bach SJ  McAllister TA  Veira DM  Gannon VP  Holley RA 《The Canadian veterinary journal. La revue veterinaire canadienne》2002,43(9):718-719

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Where the journal is going is more important than where it stands          下载免费PDF全文

Doug Hare 《The Canadian veterinary journal. La revue veterinaire canadienne》2007,48(12):1217-1218

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骨骼矿物质密度和产蛋鸡管理     

Doug Korver 《中国家禽》2007,29(20):36-37

随着家禽业的快速发展,蛋鸡的产蛋量有了很大提高,同时对产蛋鸡的健康和福利也产生很大的影响.在一天之内,当日粮提供的钙不能满足形成蛋壳所需时,钙将从骨骼中释放.而骨质疏松症的产生正是骨质随时间慢慢损失的一个过程.……  相似文献