Use of a controlled-release albendazole capsule in goats     

NC SANGSTER  JM RICKARD  GH COLLINS  DR HENNESSY  JW STEEL 《Australian veterinary journal》1992,69(3):67-68

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Evaluation of the efficacy of doramectin against an artificial infection of Dictyocaulus viviparus in calves     

Whelan NC  Charleston WA  Pomroy WE  Alexander AM 《New Zealand veterinary journal》1995,43(1):21-22

Three groups of eight Friesian calves, reared parasite-free, were experimentally infected with 1000 infective larvae of Dictyocaulus viviparus. Two groups were injected subcutaneously with 1% doramectin at 0.2 mg/kg body weight, one group 5 days after infection and the other 25 days after infection. A third group served as untreated controls. Faecal samples were examined for lungworm larvae on days 28, 32, 33, 34 and 35 after infection; the calves were killed and necropsied 39 or 40 days after infection and any lungworms present recovered and counted. Doramectin proved 100% effective against both 5-day-old and mature D. viviparus infections.  相似文献   

In vitro analysis of antiangiogenic activity of fungi isolated from clinical cases of equine keratomycosis     

Welch PM  Gabal M  Betts DM  Whelan NC  Studer ME 《Veterinary ophthalmology》2000,3(2-3):145-151

OBJECTIVE: The goal of this project was to explore the possibility that fungal organisms produce metabolites that inhibit angiogenesis. Procedures Fungal cultures were obtained from cases of keratomycosis, grown in Sabouraud's dextrose broth, and sterile filtered for use in experiments. The Matrigel assay was used to screen the filtrate samples for antiangiogenic activity. Matrigel is a basement membrane matrix that supports the differentiation of human umbilical vein endothelial (HUVE) cells into a capillary-like network of tubules. HUVE cells were cultured using standard techniques and passaged at confluence, with all cells being used at passage 3-6. HUVE cells (40 000 cells) were pipetted into each well of a 24-well tissue-culture plate coated with Matrigel. An aliquot of fungal media filtrate was added to each well and the plates allowed to incubate for 18 h, at which time they were evaluated for tubule formation. RESULTS: Two fungal isolates showed inhibition of tubule formation. The addition of 100, 200 and 400 &mgr;L of the fungal media filtrate from the first isolate (Fusarium sp. 99A34574) produced a consistent and dose-dependent inhibition of tubule formation. The second isolate (Aspergillus sp. 271599) did not show inhibition of tubule formation with 100 or 200 &mgr;L added to the wells, however, it did show inhibition at 400 &mgr;L/well. The remaining three isolates did not cause inhibition at any concentration. CONCLUSIONS: Our findings suggest that certain fungal organisms produce metabolites that inhibit tubule formation in vitro, and that these metabolites may play a significant role in altering the host vascular response to fungal infections of the cornea.  相似文献   

Time series analysis of forest carbon dynamics: recovery of Pinus palustris physiology following a prescribed fire     

G. Starr  C. L. Staudhammer  H. W. Loescher  R. Mitchell  A. Whelan  J. K. Hiers  J. J. O’Brien 《New Forests》2015,46(1):63-90

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Identifying crop yield gaps with site- and season-specific data-driven models of yield potential     

Filippi  Patrick  Whelan  Brett M.  Vervoort  R. Willem  Bishop  Thomas F. A. 《Precision Agriculture》2022,23(2):578-601

Precision Agriculture - There is considerable interest and value in identifying the gap between crop yields that have actually been achieved, and yields that could have potentially been achieved. A...  相似文献   

Identification and breeding behaviour of a major deletion of chromosome 5D ofTriticum aestivum     

M. D. Atkinson  E. D. P. Whelan  T. E. Miller 《Euphytica》1995,84(3):189-195

Summary A study was undertaken to evaluate the breeding behaviour and to identify a spontaneously produced putative chromosomal deletion in the winter wheat (Triticum aestivum L. em. Thell.) cv Norstar. Male and female transmission studies of plants heterozygous for the deletion chromosome indicated 9.5% and 48.8% transmission through the pollen and the egg, respectively. Meiotic analyses of progeny from deletion heterozygotes indicated that the deletion chromosome was eliminated from half of the plants, which agreed with the male and female transmission frequencies. Testcrosses of the deletion chromosome with telocentrics and nullisomic-tetrasomic combinations suggested that the deletion involved the long arm of chromosome 5D. This was confirmed by restriction fragment length polymorphism (RFLP) analysis. Also, monosomic plants obtained in progeny of deletion heterozygotes were shown to be monosomic for 5D. Studies of plants homozygous for the deletion showed relatively normal pairing between the deletion chromosomes, and with the short arm (5DS), but not the long arm (5DL). Deletion homozygotes were self-sterile, and morphologically similar to plants nullisomic for 5D, but plants that also contained 5DL, or a homoeologous chromosome were self-fertile and had normal morphology. Studies of chromosome morphology indicated that the deletion chromosome was metacentric, and the length of the long arm was reduced by approximately 60%. RFLP studies showed that, in terms of genetic distance, 90% of the arm was missing.  相似文献   

A new source of cytoplasmic male sterility in sunflower     

Ernest D. P. Whelan 《Euphytica》1980,29(1):33-46

Summary Interspecific substitutions of the nucleus of Helianthus annuus (2n=34) cv. Saturn into the cytoplasm of H. petiolaris (2n=34) by successive backcrossing, resulted in progenies with indehiscent anthers containing white, rather than normal yellow, pollen. Further backcrossing by cv. Saturn failed to restore pollen shed, suggesting that the male sterility was cytoplasmic. In vivo germination tests of pollen from 23 such plants from eight BC₅ lines, indicated complete pollen sterility for 14 plants, but normal seed set, suggesting that female fertility was not affected. Meiosis in all plants examined was normal.Crosses between seven sources of pollen-fertility restorer, one collection of wild H. annuus, and an existing source of cytoplasmic male sterility, resulted in a high frequency of plants with normal pollen shed in all F₁ progenies. However, no normal pollen shed was evident in F₁ progenies for similar crosses between BC₅ male-steriles and three of the seven restorer sources, nor for the single wild H. annuus evaluated. The foregoing suggests that the backcross substitution lines are a new source of cytoplasmic male sterility. The inheritance of restoration of pollen shed was complex and not fully elucidated. Some data suggested that two independent, complementary, dominant genes were required, but others indicated two to three independent, dominant genes.  相似文献   

A High-Temperature Electrical Conduction Mechanism in the Lower Mantle Phase (Mg,Fe)1-xO     

DP Dobson  NC Richmond  JP Brodholt 《Science (New York, N.Y.)》1997,275(5307):1779-1781

Measurements of electrical conductivity at high pressure and temperature were taken on the lower mantle phase magnesiowustite with varying Fe3+ content. Although previous measurements at atmospheric pressure suggest Fe2+-Fe3+ hopping (small polaron) as the dominant conductivity mechanism, the present experiments show a change in charge transport mechanism with temperature. The lower temperature measurements are consistent with small polaron conduction, but at higher temperatures, which are more applicable to the lower mantle, a large polaron mechanism is suggested. Because these mechanisms have different temperature and compositional dependencies, this transition has important implications for extrapolation to mantle conditions.  相似文献   

A Parametric Transfer Function for Grain-Flow Within a Conventional Combine Harvester     

Whelan  Brett M.  McBratney  Alex. B. 《Precision Agriculture》2002,3(2):123-134

Grain yield monitoring is an integral tool in the Precision Agriculture management system. When used in conjunction with a satellite-based navigation system, it provides spatial information on output variability, output response to managed inputs and is used to identify limiting resources in the crop production process. Accurately matching measured yield quantities with spatial units within a field is therefore important. At present, a simple linear time shift is employed by all commercial monitoring systems to account for the delay between GPS recorded positions and subsequent yield measurements. This study examines the internal process of grain transport to the sensor by monitoring the flow of strategically coloured grain. The flow is shown to be significantly influenced by mixing induced by threshing and auger transport processes. In contrast to the common assumption that grain moves as a spatially related cohort through to the sensor, the results suggest that a diffusion process is more realistic. A parametric model for the diffusion process is provided which suggests that from each individual yield measurement a maximum 20% of the mass could be assigned to a single spatial unit of the size that is typically allocated. The results imply that for further analyses, the inconclusive spatial origin and artificially smoothed quantities of instantaneous yield measurements should be considered.  相似文献   

Does kriging predict weed distributions accurately enough for site‐specific weed control?   总被引：1，自引：0，他引：1  

L J Rew  B Whelan  & A B Mcbratney 《Weed Research》2001,41(3):245-263

Numerous studies have demonstrated the patchy distribution of weeds within fields. The majority of these studies have used discrete sampling, recording weed densities at the intersections of regular grids. In this study, Avena spp. seedlings were recorded on square grids at four sites. The data were then divided into test and real data sets using the whole, two-thirds and one-half of the data to evaluate the consistency of global variogram models and accuracy of ordinary kriging estimates. Kriging provided poor weed density estimates at both very low and high densities, i.e. data were smoothed when compared with true values. Grid sampling took considerable time and, therefore, money to complete, whereas continuous sampling with multispectral imagery (performed at one site) was much quicker and at a finer resolution. It is suggested that sampling systems that collect continuous rather than discrete data are currently more appropriate for site-specific weed management.  相似文献