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本研究在日粮中添加精氨酸(L-Arg)和钙阻滞剂维拉帕米,旨在探讨L-Arg通过钙信号对小鼠宫内发育迟缓(IUGR)的影响。将160只雌性小白鼠随机分为4组,对照组饲喂基础日粮,L-Arg组、钙阻滞剂组、L-Arg+维拉帕米组分别在基础日粮中添加0.5%L-Arg、8 mg/kg维拉帕米、0.5%L-Arg+8 mg/kg维拉帕米。在妊娠第10、12、14、16天颈部放血处死母鼠,剖腹取胎鼠、子宫和胎盘等样品,测定相关指标,取14 d母鼠子宫固定于Carnoy’s和多聚甲醛中,分别用作肥大细胞(MC)、HE和免疫组化染色。结果表明:Arg组胎鼠数量、胎鼠体重等IUGR指标显著高于对照组(P0.05),维拉帕米组显著或极显著低于Arg组(P0.05或P0.01);L-Arg组子宫MC数显著低于对照组(P0.05),极显著低于维拉帕米组(P0.01);Arg组子宫巨噬细胞数较对照组显著增多(P0.05),维拉帕米组较对照组显著减少(P0.05),Arg组与维拉帕米组差异极显著(P0.01);L-Arg组子宫微血管(MVD)数较对照组显著增多(P0.05),较维拉帕米组显著减少(P0.05)。综上,L-Arg通过调控MC释放介质来提高母鼠的繁殖能力,维拉帕米能阻止Arg该作用,表明L-Arg通过钙信号发挥生物学作用,是其缓解IUGR的机理之一。 相似文献
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Landscape Zonation, benefit functions and target-based planning: Unifying reserve selection strategies 总被引:1,自引:0,他引:1
Atte Moilanen 《Biological conservation》2007,134(4):571-579
The most widespread reserve selection strategy is target-based planning, as specified under the framework of systematic conservation planning. Targets are given for the representation levels of biodiversity features, and site selection algorithms are employed to either meet the targets with least cost (the minimum set formulation) or to maximize the number of targets met with a given resource (maximum coverage). Benefit functions are another recent approach to reserve selection. In the benefit function framework the objective is to maximize the value of the reserve network, however value is defined. In one benefit function formulation value is a sum over species-specific values, and species-specific value is an increasing function of representation. This benefit function approach is computationally convenient, but because it allows free tradeoffs between species, it essentially makes the assumption that species are acting as surrogates, or samples from a larger regional species pool. The Zonation algorithm is a recent computational method that produces a hierarchy of conservation priority through the landscape. This hierarchy is produced via iterative removal of selection units (cells) using the criterion of least marginal loss of conservation value to decide which cell to remove next. The first variant of Zonation, here called core-area Zonation, has a characteristic of emphasizing core-areas of all species. Here I separate the Zonation meta-algorithm from the cell removal rule, the definition of marginal loss of conservation value utilized inside the algorithm. I show how additive benefit functions and target-based planning can be implemented into the Zonation framework via the use of particular kinds of cell removal rules. The core-area, additive benefit function and targeting benefit function variants of Zonation have interesting conceptual differences in how they treat and trade off between species in the planning process. 相似文献
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基于小波变换的Wiener滤波算法去除苹果图像噪声 总被引:1,自引:1,他引:1
在小波变换的基础上,提出了一种基于小波变换的Wiener滤波去噪方法。采用该方法对苹果图像的加性噪声(高斯白噪声)去噪,结果PSNR为184.94,视觉效果清晰(而含噪声图像的PSNR为158.23,噪声太多不清晰)。好于邻域平均法(PSNR为174.15,视觉上含部分噪声)、中值滤波法(PSNR为182.4Z)、小波阔值去噪(PSNR为171.59,视觉上也含部分噪声)和Wiener滤波去噪法(PSNR为173.65)的去噪结果,更好于数学形态学的去噪结果(PSNR为150.46,视觉上含较多噪声)。试验结果表明,基于小波变换的Wiener滤波方法对苹果图像加性噪声的去噪效果具有信噪比高、视觉效果好等优点。 相似文献
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供试肉猪78头,随机分为三组,对照组(空白)、试验1组(新霉素115mg/kg、喹乙醇100mg/kg、阿散酸100mg/kg)、试验2组(JX调理剂0.2%),试验结果表明:第一阶段:试验1、2期末重,分别比对照组高1.34kg、1.07kg(P<0.05),试验组间差异不显著(P>0.05);第二阶段:试验1组期末重,比对照组高2.65kg(P>0.05),试验2组期未重比对照组高3.23kg(P<0.05),试验组间差异不显著(P>0.05);试验组料肉比均低于对照组,试验2组最低,比对照组降低0.2,饲料转化效率提高8.97%;试验2组比对照组每头猪多盈利48.8元,比试验1组多盈利10.28元;粪便中氮、磷含量试验2组明显下降,药物残留试验2组、对照组没有检出,试验1组猪肝阳性3个加、肉中阳性1个加。 相似文献
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AIM:To observe changes of serum asymmetry dimethylarginine (ADMA) and endothelin-1 (ET-1) levels,which reflect blood vessel endothelial function,after therapy of enhanced external counterpulsation(EECP) in patients who had taken percutaneous transluminal coronary angioplasty and stent.METHODS:Fifty one coronary heart disease patients (all of them had taken percutaneous tranluminal coronary angioplasty and stent) were distributed into two groups by matching them with ratio of 1∶2,17 patients in EECP group and 34 patients in control group.Both of two groups were given conventional medicine,in addition,EECP group was undertaken three courses of treatment of EECP.ADMA was detected by HPLC-fluorescence method,and ET-1 was detected by radio-immunity method.RESULTS:In EECP group ,compared with prior treatment,ADMA and ET-1 levels was obviously reduced (P<0.05).In control group,compared with prior treatment,ADMA had no significant difference (P>0.05) and ET-1 was higher (P<0.01).Compared between two groups,extent of decrease in ADMA and ET-1 levels in EECP group were more obvious than control group (P<0.01).Improvement of angina and decrease of frequency of angina was more obvious in EECP group than control group.Besides,decrease of ADMA level was positive correlation with them (r=0.85,0.70,respectively P<0.01).CONCLUSION:EECP reduces serum ADMA and ET-1 levels by increasing shear stress to vessel endothelium in coronary heart disease patients who had taken percutaneous tranluminal coronary angioplasty.It hints that EECP can improve endothelial function and provides experimental evidence for the combined treatment of coronary heart disease. 相似文献
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新型激活蛋白对多种作物种子发芽的影响 总被引:1,自引:0,他引:1
为探讨真菌源激活蛋白在促进种子发芽方面的效果,研究了不同浓度激活蛋白处理对多种作物种子的影响。试验结果表明,用2—3μg/mL的新型激活蛋白浸泡棉种6h,能显著提高种子的发芽势和发芽率。番茄和丝瓜种子分别用1μg/mL的蛋白浸种6h,能显著提高种子的发芽率。黄瓜种子用500倍和1000倍液都能显著提高种子的发芽率。 相似文献
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生物试验的二次回归正交试验的模糊处理 总被引:3,自引:1,他引:2
通过抗寒促生长剂对雏鸡生长,成活效果的试验,采用模糊处理方法,来探讨具有多项试验结果指标的二次回归正交试验设计的结果处理方法。 相似文献
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本文针对掺加不同外加剂的混凝土的含气量、抗冻性能、抗压强度、抗折强度等方面的试验研究,提出掺入外加剂是提高水泥混凝土路面耐久性的必要措施。 相似文献