排序方式: 共有124条查询结果,搜索用时 31 毫秒
1.
AIM: To investigate the pathogenesis of chronic obstructive disease (COPD) in mice by using nasal drip of cigarette dust particles (DSP) induced pulmonary function damage model.METHODS: BALB/c mice were randomly divided into control group, LPS 100 mg/L group, DSP 0.75 mL/L group, DSP 1.5 mL/L group and DSP 3 mL/L group for 30 days. The method of nasal drip was used for 30 days to establish the COPD model. Rrs, Ers, Crs, Est, Cst, P-3/8Rn, P-3/8G and P-3/8H were measured for evaluating lung function of the mice in each group by the method of FlexiVent. The effect on the increase of airway resistance induced by methacholine (Mach) was determined using main bronchial rings by Myograph method. The HE, Masson and Resorcinol fuchsin staining of mouse tracheas and lung tissues were conducted. RESULTS: Continuous nasal drip with DSP for 30 days increased Rrs, Ers, Est, P-3/8Rn and decreased Crs, Cst, P-3/8G and P-3/8H in the mice. DSP significantly shifted the dose-effect curve of tracheal contraction induced by Mach to the left, increased the sensitivity of the airway to Mach, and significantly increased the maximal contractile airway effect of Mach. Exposure to DSP caused fibrosis of airway subepithelial, deposition of collagen in the airway basement membrane under the reticular plate, induced reticular plate thickening, pulmonary bronchial lumen serious deformation, and the inflammatory cell infiltration in the lung of mice. Significantly increased alveolar wall muscle fibers and collagen fibers were also observed. CONCLUSION: The lung function and pathomorphological changes of COPD mice induced by 30 days nasal drip of cigarette dust particles were similar to those of human COPD. 相似文献
2.
[目的]优化KDF-2滤棒成型机加工工艺参数,提高滤棒成型质量的稳定性。[方法]以对滤棒加工质量有重要影响的工艺参数:辊速比、辊压力、喷嘴空气压力、增塑剂施加量为试验因子,采用4因素3水平正交试验,并对滤棒分切前后的压降变化进行了研究。[结果]滤棒成型的最佳工艺参数组合为:增塑剂施加量9%、喷嘴空气压力0.40 MPa、辊速比1∶1.28、辊压力0.20、0.20、0.050 MPa,对滤棒质量影响最大的指标为增塑剂施加量。将滤棒分切至目标长度后,切前压降比切后4支短支总和平均低44 Pa,并且切后4支滤嘴压降差异较大,极差平均为80 Pa。[结论]研究可为优化滤棒成型工艺参数、提高滤棒质量提供参考。 相似文献
3.
[目的]探索卷烟滤嘴中三醋酸甘油酯向卷烟主流烟气的转移情况。[方法]将4种施加了不同含量的三醋酸甘油酯滤棒切成4份作为滤嘴卷制卷烟,考察卷烟滤嘴中三醋酸甘油酯的含量与其卷烟制品主流烟气中的三醋酸甘油酯含量的关系。[结果]随着滤棒的三醋酸甘油酯施加比例从3.06%增加到10.35%,三醋酸甘油酯转移到烟气中的量也随之提高,但转移率却由10.41%下降到4.43%。[结论]该研究为了解滤嘴中三醋酸甘油酯在卷烟主流烟气中的转移情况提供了依据。 相似文献
4.
5.
6.
[目的]研究吡咯烷酮羧酸钠对降低卷烟气中亚硝胺的释放量的影响.[方法]对添加吡略烷酮羧酸钠的卷烟的感官指标、物理指标和化学指标进行评价.[结果]与对照烟相比,添加吡咯烷酮羧酸钠的卷烟在香气、刺激性、协调性、杂气和余味等感官指标上有较大的改善;在重量、吸阻、圆周、园度和硬度等物理指标上无明显变化;在焦油、一氧化碳、烟碱、N-亚硝胺等化学指标上均有所降低.[结论]吡咯烷酮羧酸钠对降低卷烟气中焦油、一氧化碳、烟碱、N-亚硝胺等有害成分有一定的效果. 相似文献
7.
[目的]研究膨胀温度对卷烟主流烟气中7种Hoffmann成分(CO、NNK、NH3、HCN、BaP、巴豆醛、苯酚)释放量的影响。[方法]采用不同膨胀温度处理后的烟丝卷制卷烟,测定其烟气中7种Hoffmann成分的释放量。[结果]同一膨胀模式下,温度变化对NH3、苯酚和BAP的释放量有一定影响,对CO、NNK、HCN和巴豆醛则无显著影响;CO2膨胀方式下7种Hoffmann成分的释放量较小;降低膨胀温度在一定程度有利于降低卷烟危害性指数。[结论]该研究为低危害卷烟工艺设计参数的优化选择提供了依据。 相似文献
8.
简述了微胶囊制备方法和烟用香料微胶囊化的主要作用,着重探讨了微胶囊技术在烟丝加香、滤嘴、卷烟纸、再造烟叶和新型烟草制品方面的研究现状。 相似文献
9.
10.
烟碱量与烟气烟碱量的相关分析与回归预测 总被引:2,自引:2,他引:0
为了细致阐述烟叶原料和卷烟产品中烟碱量与烟气烟碱量之间的相互关系。以云南省17个县市收集的148个单料烟质量检测数据和全国14家卷烟厂中2个卷烟品牌各自的107、209个检测数据为材料,对烟碱量和烟气烟碱量2个指标进行相关、回归分析并通过回归方程进行预测。结果表明,A品牌中烟气烟碱量与烟碱量之间的相关系数为0.858,以烟碱量作为反应变量得到回归方程为:y^=0.741+1.186x;以烟气烟碱作为反应变量得到回归方程为:y^=-0.134+0.621x。2项指标预测偏差绝对值分别为:烟碱量0.042%~3.04%;烟气烟碱量0.22%~6.51%。B品牌中烟气烟碱与烟碱量之间的相关系数为0.754,以烟碱量作为反应变量得到回归方程为:y^=1.106+0.946x;以烟气烟碱量作为反应变量得到回归方程为:^y=-0.204+0.601x。2项指标预测偏差绝对值分别为:烟碱量0.29%~6.22%,烟气烟碱量0.91~9.70%;单料烟中烟气烟碱与烟碱量之间的相关系数为0.940,以烟碱量作为反应变量得到回归方程为:y^=0.283+1.032x;以烟气烟碱作为反应变量得到回归方程为:y^=0.028+0.856x。2项指标预测偏差绝对值分别为:烟碱量0.016%~20.37%;烟气烟碱量0.084%~18.5725%。说明烟叶原料和卷烟成品都可以从烟气烟碱量与烟碱量两者间建立较好的回归模型,且能满足预测精度要求。 相似文献