Computed Tomographic Angiography of the Pancreas in Cats with Chronic Diabetes Mellitus Compared to Normal Cats          下载免费PDF全文

S. Secrest  A. Sharma  A. Bugbee 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2018,32(3):962-966

Background

Diabetes mellitus (DM) is a common endocrinopathy in cats. No known diagnostic test or patient characteristic at the time of diagnosis can predict likely disease course, unlike in people in whom computed tomographic angiography (CTA) is used. No published data exist regarding the CTA appearance of the pancreas in cats with DM, and thus, it is unknown what if any CTA variables should be further assessed for associations with pancreatic endocrine function.

Hypothesis/Objectives

A significant difference in pancreatic attenuation, volume, and size will be identified between normal cats and those with chronic DM on CTA.

Animals

Ten healthy control cats and 15 cats with naturally occurring DM present for >12 months.

Methods

Prospective cross‐sectional study comparing pancreatic attenuation, enhancement pattern, size, volume, pancreatic volume‐to‐body weight ratio (V:BW), pancreatic arterial: portal phase ratio (A:P), time‐to‐arterial enhancement, and time‐to‐peak portal enhancement on CTA between sedated healthy control cats and those with chronic DM.

Results

The pancreas in cats with chronic DM was significantly larger, had higher volume, higher V:BW, and shorter time‐to‐peak portal enhancement on CTA when compared to normal cats.

Conclusions and Clinical Importance

Peak portal enhancement time, pancreatic size, pancreatic volume, and V:BW can be used to differentiate normal sedated cats from those with chronic DM by CTA. These variables warrant further investigation to identify possible associations with endocrine function.  相似文献   

Initial analytic quality assessment and method comparison of an immunoassay for adrenocorticotropic hormone measurement in equine samples          下载免费PDF全文

Katherine L. Irvine  Kay Burt  Andrew J. Hill  Stephanie Shaw  Kostas Papasouliotis 《Veterinary clinical pathology / American Society for Veterinary Clinical Pathology》2016,45(1):154-163

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Catecholamine Metabolism in a Shetland Pony with Suspected Pheochromocytoma and Pituitary Pars Intermedia Dysfunction          下载免费PDF全文

N. Fouché  V. Gerber  D. Gorgas  V. Marolf  E. Grouzmann  J.H. van der Kolk  C. Navas de Solis 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2016,30(6):1872-1878

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Advance in study of batokines     

YAN Jia-Hui  HAN Liang  CHEN Guang 《园艺学报》2020,36(6):1140-1145

Brown adipose tissue is a type of adipose tissue and is present in all mammals. It is not only the main site for adaptive thermogenesis in vivo, but also secretes and releases many cytokines in the form of endocrine to regulate a variety of metabolic processes and prevent and treat obesity and metabolic diseases. Therefore, identification of the types and effects of brown adipocytokines (batokines) may be crucial for the treatment of a variety of obesity-related metabolic diseases. Based on the latest research progress, batokines and their functions are reviewed.  相似文献   

酵母铬对热应激蛋用种公鸡精液品质的影响及作用机制研究     

程玉芳 《安徽农业科学》2007,35(10):2920-2921

选用72只35周龄罗曼种公鸡随机平均分成6组,对照组饲喂基础日粮,分别在基础日粮中添加0.2、0.4、0.6、0.8、1.0 mg/kg铬量的酵母铬,作为试验I、II、III、IV、V组来探讨酵母铬对热应激蛋用种公鸡精液品质及内分泌机能的影响.结果表明:与对照组相比,日粮中添加0.4、0.6、0.8、1.0 mg/kg铬量的酵母铬均不同程度提高公鸡的精液量、精子活力和精子密度,降低公鸡精液的精子畸形率,而对精液的pH值影响不明显;试验各组公鸡血浆三碘甲腺原氨酸(T3)水平均有不同程度升高;皮质醇、甲状腺素 (T4)水平降低.上述结果表明:在热应激条件下,日粮中添加一定量的酵母铬可有效缓解热应激,显著提高夏季蛋用种公鸡的繁殖性能并影响其内分泌机能.  相似文献   

Endocrine differentiation and its mechanism in endometrial carcinoma     

LU Xiao-ye  WANG Zi-neng  HUANG Zhong-xin  QIN Li 《园艺学报》2003,19(6):792-794

AIM:To investigate endocrine differentiation and its mechanism in endometrial carcinoma.METHODS:Endocrine cells (EC) were identified by immunohistochemical staining of chromogranin A in 50 cases of endometrioid adenocarcinoma and 20 cases of normal endometrium. Double-label techniques were used for simultaneous demonstration of the CgA and cytokeratin.RESULTS:The positive rate of CgA in endometrioid adenocarcinoma was 44.0%, and was significant higher than that in normal endometrium (15.0%, P＜0.05). Scanty EC was present in normal endometrium. The number and staining intensity of EC in endometrioid adenocarcinoma were greater than that in normal. Co-expression of CgA and cytokeratin were detected in endometrioid adenocarcinoma.CONCLUSION:The presence of endocrine cells in endometrioid adenocarcinoma showed heterogeneity of tumors. The occurrence of "Multidirectional differentiation cells" within the endometrioid adenocarcinoma may indicate that endocrine cells derive from malignant cells of multidirectional differentiation.  相似文献   

提高畜禽生产力的新技术研究     

黄运茂  李孝伟  施振旦 《安徽农业科学》2007,35(5):1532-1533

综述了提高畜禽生产力的新技术.分别为:改变循环系统或组织中生长激素浓度;改变生长激素生物效能促进动物生长和泌乳;基因"敲除"技术和动物克隆技术.  相似文献   

Parathyroid hormone‐related protein‐induced hypercalcemia due to osteosarcoma in a cat          下载免费PDF全文

Masashi Yuki  Makiko Nitta  Tetsuo Omachi 《Veterinary clinical pathology / American Society for Veterinary Clinical Pathology》2015,44(1):141-144

A 15‐year‐old castrated male mixed‐breed cat was presented with a history of sarcoma of the distal right hind limb. Biochemical analysis revealed increased concentrations of blood urea, creatinine, total calcium, ionized calcium, and parathyroid hormone‐related protein (PTHrP). The mass was removed surgically by amputation of the hind limb. Osteosarcoma was diagnosed based on histopathologic examination. All abnormal serum analyte concentrations improved immediately after surgery, including azotemia, total calcium, ionized calcium, and PTHrP. The biochemical results were attributed to osteosarcoma causing PTHrP‐induced hypercalcemia.  相似文献   

A comparison of the survival times of dogs treated with mitotane or trilostane for pituitary-dependent hyperadrenocorticism     

Barker EN  Campbell S  Tebb AJ  Neiger R  Herrtage ME  Reid SW  Ramsey IK 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2005,19(6):810-815

The survival times of 148 dogs treated for pituitary-dependent hyperadrenocorticism were studied using clinical records from 3 UK veterinary centers between 1998 and 2003. Of these animals, 123 (83.1%) were treated with trilostane, while 25 (16.9%) were treated with mitotane. Treatment groups were compared using t-tests and analysis of variance (or their nonparametric equivalents) and chi-square tests. Survival data were analyzed using Kaplan-Meier survival plots and Cox proportional hazard methods. There was no significant difference between the population attributes from each center or between treatment groups. The median survival time for animals treated with trilostane was 662 days (range 8-1,971) and for mitotane it was 708 days (range 33-1,399). There were no significant differences between the survival times for animals treated with trilostane and those treated with mitotane. In the multivariable model (including drug, center, breed group, weight, diagnostic group, and age at diagnosis), only age at diagnosis and weight were significantly negatively associated with survival. Importantly, there was no significant effect of drug choice on survival.  相似文献   

Seasonal changes in the combined glucose-insulin tolerance test in normal aged horses     

Funk RA  Wooldridge AA  Stewart AJ  Behrend EN  Kemppainen RJ  Zhong Q  Johnson AK 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2012,26(4):1035-1041

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