THE INSENSITIVITY OF ^99mTc PERTECHNETATE FOR DETECTING METASTASES OF A FUNCTIONAL THYROID CARCINOMA IN A DOG     

Michael R.  Broome  DVM  MS  Gayle S.  Donner  DVM 《Veterinary radiology & ultrasound》1993,34(2):118-124

This report describes the use of ^99mtechnetium pertechnetate (^99mTcO₄⁻) and ¹³¹[for imaging of a metastatic thyroid carcinoma in a dog. The ¹³¹] imaging showed metastatic lesions undetected by the ^99mTcO₄⁻ imaging on 2 separate occasions. The possible mechanisms for the discrepancies between ¹³¹I and ^99mTcO₄⁻ imaging of thyroid carcinomas are discussed. The use of ¹³¹I for the imaging of functional thyroid carcinomas in the dog is recommended.  相似文献   

THE NON-CARDIAC DISTRIBUTION OF ^99mTC-METHOXY-ISOBUTYL-ISONITRILE (SESTAMIBI) IN NORMAL BEAGLES     

Phillip F.  Steyn  BVSc  MRCVS  MS  Gregory  Ogilvie  DVM 《Veterinary radiology & ultrasound》1995,36(2):160-163

Technetium-99m methoxy-isobutyl-isonitrile (sestamibi) is a radiophartnaceutical used for the evaluation of myocardial perfusion. Increased uptake of sestamibi has also been documented in tumors. The objective of this study was to document the extracardiac biodistribution of ^99mTc sestamibi in the normal dog. Nine normal beagles were given 0.35 mCi/kg ^99mTc sestamibi intravenously, and 60 second images were made of the entire body at 1 hour post injection. A defined distribution pattern was recognized, with good visualization of the heart, liver, gallbladder, small intestine, kidneys, urinary bladder, popliteal lymph nodes, parotid salivary glands and zygomatic salivary glands. Splenic uptake was not seen.
Target to background ratios were calculated for all the regions listed, using background regions-of-interest with the smallest coefficient of variance for the denominator. The mean, range and standard deviation of these ratios are given.  相似文献   

Diagnosis of Congenital Cardiac Right-to-left Shunts with ^99mTc-macroaggregated Albumin     

Federica Morandi  DVM  MS    Gregory B. Daniel  DVM  MS    Rebecca E. Gompf  DVM  MS    Anne Bahr  DVM  MS 《Veterinary radiology & ultrasound》2004,45(2):97-102

Diagnosing right-to-left congenital cardiac shunts can be difficult. Cardiac catheterization and angiocardiography represent the traditional gold standard for diagnosis, but they are invasive. Nuclear scintigraphy using 99mTc-macroaggregated albumin (MAA) has been employed in humans as an alternate method of diagnosis. This study reviews eight dogs presented for evaluation of a suspect right-to-left cardiac shunt that were examined using 99mTc-MAA. In all, 2-4 mCi (74-148 MBq) of reduced particle 99mTc-MAA were injected IV in a cephalic vein and static images of the whole body, including right and left lateral, dorsal, and ventral views, were acquired for 60 s and stored into a 256 x 256 x 16 matrix. Shunt fractions were calculated. One dog with radiopharmaceutical distribution limited to the lungs did not have a shunt. Seven dogs had distribution of the radiopharmaceutical outside the pulmonary capillary bed, indicating bypassing of the pulmonary capillary circulation due to a right-to-left shunt. Four dogs had 99mTc-MAA within the brain. Three dogs that did not have brain uptake, but instead had a sharp cutoff of radioactivity at the level of the front limbs and neck, were diagnosed with reverse patent ductus arteriosus (PDA). The asymmetric distribution of the radiopharmaceutical is due to the location of the shunt, distal to the brachiocephalic trunk and left subclavian artery. Shunt fractions of dogs with extrapulmonary radioactivity ranged from 40% to 59%. Nuclear scintigraphy with 99mTc-MAA is a quick alternative method of diagnosing right-to-left cardiac shunts that permits quantification of shunt fraction. Distinguishing between reverse PDA and other right-to-left shunts may be possible based on the radiopharmaceutical distribution.  相似文献   

仔猪黄痢K88-K99-987p-F41多价菌毛疫苗的制备及小鼠免疫试验   总被引：2，自引：0，他引：2  

李鹏  王家乡  程碧军 《动物医学进展》2006,27(9):55-58,96

为了更好地预防仔猪黄痢,选取野生分离菌株HN2001（K88ab）、HN2002（K88ac）、HN2003（K88ad）、HN2004（K99）、HN2005（987p）和HN2006（F41）培养后用低温磁力搅拌法提取菌毛,制成5批多价菌毛混合油乳剂灭活苗。试验结果表明,5批多价灭活疫苗对小鼠的平均保护率达95．0％,为进一步进行本体动物试验提供了有价值的参考资料。  相似文献   

大肠埃希氏菌表面菌毛黏附因子多价菌毛疫苗的研制     

李鹏  王家乡  程碧军 《湖北农业科学》2006,45(5):643-646

为了预防仔猪黄痢,选取ETEC野生分离菌株HN2001(K88ab)、HN2002(K88ac)、HN2003(K88ad)、HN2004(K99)、HN2005(987p)、HN2006(F41)培养后用低温磁力搅拌法提取到菌毛,制成5批多价菌毛混合油乳剂灭活苗,实验室试验结果表明,5批多价灭活疫苗对小白鼠的平均保护率达95.0%,为进一步进行田间试验提供了理论依据,并将为生产上防治仔猪黄痢提供一种保护范围更加全面的生物制品.  相似文献   

高产高蛋白食饲两用早籼99早677的选育及其栽培技术     

郑瑞丰  曾德洪  李茂扬 《湖南农业科学》2006,(1):15-16

99早677系湘早籼19号与湘早籼24号配组杂交,经9 a选育而成,2004年2月通过湖南省农作物品种审定委员会审定命名.该品种全生育期110 d左右,一般产量7.2～7.6 t/hm2,抗白叶枯病,适合湖南全省各地作食饲两用早稻栽培.栽培技术要点密度13.3 cm×20.0 cm,全生育期施纯氮180 kg/hm2,氮磷钾比例为111.2.  相似文献   

3个豇豆株系的性状观察比较试验     

彭友林  王云 《长江蔬菜》2009,(22)

对豇豆99-2,99-3,99-4三个优良株系性状进行比较试验.结果表明,豇豆99-2具有生长势好、早熟、高产、优质、商品性好等特点,丰产性尤为突出;前期产量12 304.5 kg/hm2,占总产量33 949.5 kg/hm2的36.68%,鲜荚比99-3、99-4早2～3 d上市.可作为早熟品种推广栽培.  相似文献   

一种非EDSV引起的鸭传染性减蛋症   总被引：5，自引：1，他引：5  

何永强  杜青云  盛祖恬  孙理云 《浙江农业学报》2001,13(3):125-126

自1999年5月以来，浙江省许多产蛋鸭发生了一种以产蛋率锐减为特征的新疾病，其中某地区67户养鸭专业户，共饲养蛋鸭15.7万羽，陆续进入产蛋高峰期后，有2375 羽鸭群的产蛋率突然下降，由原来的91.2%减到52.7%，同时伴有畸形蛋、沙壳蛋，蛋质低劣，蛋清稀薄，除少部分病鸭伴有烦躁不安和吵棚外，鸭群的精神体态基本正常，采食量略有下降，一般不引起死亡。起初养鸭户都误认为是当地饲料厂供应的饲料所致，后来发现该病具有传染性，疫病主要沿河流自上而下蔓延。在此后1个多月时间内，共有49户养鸭户12.3 万羽蛋鸭相继发病，产蛋率下降幅度为20%～80%，使用各种抗菌药物治疗无效，提高饲料营养也不起作用。该病发病急，传播迅速，通常在2～3天内产蛋率由80%～90%以上下降到30% ～40%，有的甚至更低，产蛋率越高，感染后下降幅度往往越大。病鸭从产蛋下降到康复需3 -7周时间，恢复后不能达到标准产蛋曲线，产蛋周期缩短。剖检病鸭主要表现为生殖器官病变，卵巢卵泡减少、萎缩，输卵管蛋白分泌部缩小，蛋白分泌腺减少，子宫萎缩，有的严重病例可见卵黄性腹膜炎，肝、心、肾和肺有斑点出血。该病的临床症状类似于减蛋综合征（ EDS）［1］，但是，用减蛋综合征灭活苗免疫预防不能有效保护。作者对病鸭体作无菌检查并分离了病毒（命名为YH99株），用0.2 μm滤器过滤后，经人工感染易感蛋鸭能成功诱导典型发病，再从病鸭中回收到同样病毒。将YH99株与鸡源减蛋综合征病毒（EDSV-AV127）［2～4］和鸭源减蛋综合征病毒［3］（EDSV-JE 1，由上海市畜牧兽医站周锦萍提供）进行比较，结果发现：  相似文献   

氮磷钾硫肥配施对云烟87的产量效应     

周丽丽  刘爱琴  唐莉娜  孟李群 《亚热带农业研究》2012,8(1):17-22

以福建优质烤烟云烟87为研究对象,通过四因素五水平二次通用旋转组合设计试验,进行单因子和双因子交互效应分析,探讨N、P、K、S配施对产量的影响。单因子效应分析表明,随N、s水平增加,产量先提高后下降;随K水平增加,产量先下降后提高;随P水平增加,产量提高。双因子互作效应分析表明,N×P、N×S,P×K、P×S、K×S双...  相似文献   

贵州烟区烤烟品种云烟87主要化学成分特征分析     

张丽  姬厚伟  黄锡娟  刘义萍  刘剑  何军  段凯 《安徽农业科学》2015,(20)

[目的]分析贵州主产区烤烟品种云烟87主要化学成分,掌握其特点.[方法]对贵州省主产烟区烤烟品种云烟87主要化学成分进行分析,并与云南主产区云烟87化学成分进行比较.[结果]分析表明,贵州烟区烤烟品种云烟87主要化学成分总体协调,总糖含量、还原糖含量较高,钾含量略低,糖碱比略高,总植物碱含量、氯含量、总氮含量、氮碱比、钾氯比均较适宜;钾氯比的变异系数最大,总糖和还原糖含量的变异系数最小;云烟87烤烟总糖含量、总植物碱含量和糖碱比在不同等级样品间差异显著;氯含量、钾含量和氮碱比在不同地区间差异显著.贵州云烟87样品总糖含量、氯含量显著低于云南云烟87样品,钾氯比显著高于云南云烟87样品.[结论]研究可为贵州烤烟云烟87的优质生产和合理布局提供理论依据.  相似文献