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狗舌草中毒猪血液中吡咯代谢物的测定 总被引：7，自引：1，他引：6
用含 10 %狗舌草的饲料喂猪 144d ,进行了血液S—吡咯测定。染毒后第 8～ 96d ,试验猪血液S—吡咯TLC呈现较为明显的淡紫色斑 ,Rf值在 0 5 6～ 0 78之间 ;在试验的第 8d ,试验猪血液S—吡咯光密度值达 0 0 89± 0 0 0 7OD单位 ,此后一直呈上升趋势 相似文献
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本试验应用常规石蜡切片技术,H.E染色镜检观察阿维菌素中毒犊牛的心脏、肝脏、脾脏、肺脏、肾脏、肠系膜淋巴结、空肠、瘤胃8个组织器官,结果表明:各脏器主要病理变化是出血和瘀血;心肌纤维断裂、变性坏死,间质内充满大量炎性细胞;肝脏实质细胞肿胀,脂肪变性,叶间静脉内出现均质红染浆液;肺泡内有浆液渗出;肾小管凝固性坏死,肾小球肿胀,间质内出现水肿液;淋巴结淋巴中心细胞坏死。这些器管组织的损伤变化,有助于进一步探索阿维菌素中毒的发病机制及病理特征,从而为及时对发病动物进行确诊治疗提供形态学依据。 相似文献
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经试验山羊瘤胃瘘管投放硝酸钾后1～2h瘤胃内容物NO3-急速上升，4～6h后下降至投药前水平；而NO2-却达到500～600μg／ml，伴随NO3-、NO2-消长的同时，瘤胃蠕动由减弱至停滞。可视粘膜由轻度发绀到乌紫色，血液褐变逐渐加重，最终是酱油色。血液中NO3-变化不大（P＞0．05），NO2-却明显上升，最高可达到20～30μg／ml，伴随NO2-的上升，血液中MHb／Hb比值升至72％～82％。而CO2CP明显下降，最低降至为10～11mmol／L，两组动物比较差异显著（P＜0．05）。至中毒后期（或动物死亡前）体温明显下降，可下降1～2℃。 相似文献
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Sonja Steinmetz Andrea Tipold Thomas Bilzer Henning Christian Schenk 《Irish veterinary journal》2012,65(1):19
A seven-year old Australian Shepherd, suffering from idiopathic epilepsy under treatment with phenobarbitone and potassium bromide, was presented with generalised lower motor neuron signs. Electrophysiology and muscle-nerve biopsies revealed a neuromyopathy.The serum bromide concentration was increased more than two-fold above the upper reference value.Clinical signs disappeared after applying diuretics and reducing the potassium bromide dose rate. This is the first case report describing electrophysiological and histopathological findings associated with bromide induced lower motor neuron dysfunction in a dog. 相似文献
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Mary J Canty Ursula Fogarty Michael K Sheridan Steve M Ensley Dwayne E Schrunk Simon J More 《Irish veterinary journal》2014,67(1):21
Four primary mycotoxicosis have been reported in livestock caused by fungal infections of grasses or cereals by members of the Clavicipitaceae family. Ergotism (generally associated with grasses, rye, triticale and other grains) and fescue toxicosis (associated with tall fescue grass, Festuca arundinacea) are both caused by ergot alkaloids, and referred to as ‘ergot alkaloid intoxication’. Ryegrass staggers (associated with perennial ryegrass Lolium perenne) is due to intoxication with an indole-diperpene, Lolitrem B, and metabolites. Fescue-associated oedema, recently described in Australia, may be associated with a pyrrolizidine alkaloid, N-acetyl norloline.Ergotism, caused by the fungus Claviceps purpurea, is visible and infects the outside of the plant seed. Fescue toxicosis and ryegrass staggers are caused by Neotyphodium coenophalium and N. lolii, respectively. Fescue-associated oedema has been associated with tall fescue varieties infected with a specific strain of N. coenophialum (AR542, Max P or Max Q). The name Neotyphodium refers to asexual derivatives of Epichloë spp., which have collectively been termed the epichloë fungi. These fungi exist symbiotically within the grass and are invisible to the naked eye.The primary toxicological effect of ergot alkaloid involves vasoconstriction and/or hypoprolactinaemia. Ingestion of ergot alkaloid by livestock can cause a range of effects, including poor weight gain, reduced fertility, hyperthermia, convulsions, gangrene of the extremities, and death. To date there are no published reports, either internationally or nationally, reporting ergot alkaloid intoxication specifically associated with perennial ryegrass endophytes. However, unpublished reports from the Irish Equine Centre have identified a potential emerging problem of ergot alkaloid intoxication with respect to equines and bovines, on primarily perennial ryegrass-based diets. Ergovaline has been isolated in varying concentrations in the herbage of a small number of equine and bovine farms where poor animal health and performance had been reported. Additionally, in some circumstances changes to the diet, where animals were fed primarily herbage, were sufficient to reverse adverse effects. Pending additional information, these results suggest that Irish farm advisors and veterinarians should be aware of the potential adverse role on animal health and performance of ergot alkaloids from perennial ryegrass infected with endophytic fungi. 相似文献
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本文概述了四川草地上分布的有毒野生植物的种类及其特征；介绍了各种有毒植物的中毒过程及症状、毒素成份等。对牲畜中毒后的救治提供一相应方法。 相似文献
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[目的]为了正确评价不同浓度的磺胺喹恶啉对雏鸡的生长发育和对各器官组织特别是免疫器官的影响,并分析其中毒机理。[方法]以0.2%、0.5%2个浓度剂量的复方磺胺喹恶啉钠分别给7日龄海兰褐蛋雏鸡连续饮水14d,建立磺胺喹恶啉钠雏鸡人工中毒试验模型,试验鸡只按正常免疫程序免疫新城疫,观察鸡群的临床表现,分别在用药后第7天和第14天分别剖杀试验雏鸡,称量体重,测量免疫器官指数和新城疫抗体水平,观察剖检病变及病理组织学变化,评价应用磺胺喹恶啉钠对雏鸡的影响。[结果]雏鸡饮用0.2%磺胺喹恶啉连用1周是安全的,连用2周发生轻度中毒的表现;雏鸡饮用0.5%磺胺喹恶啉很快发生中毒表现,磺胺喹恶啉中毒可使雏鸡出现严重临床症状,机体免疫机能下降,免疫器官发育受阻,抗体水平降低,肌肉出血,肝、肾等实质器官变性肿胀。[结论]该研究为正确使用磺胺喹恶啉、促进养鸡业的发展提供了依据。 相似文献
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