实验性急性猪丹毒抗原定位和病理学研究   总被引：1，自引：0，他引：1  

孙福先  宣长和 《黑龙江畜牧兽医》1993,(6):1-3

用猪丹毒强毒株人工接种试验猪,采取其心、肺、肾、肝等器官制成样品,光镜和电镜观察结果,靶器官为心、肾、脑、脾、淋巴结,猪丹毒杆菌定位在器官的微血管。  相似文献   

雏鸡实验感染柔嫩艾美尔球虫的病理学研究   总被引：5，自引：0，他引：5  

林毅  冯泽光 《畜牧兽医学报》1993,24(5):446-451

１１４只２３日龄无球虫罗斯小公鸡，分为三组，第１和第２每只鸡分别口服１．０８×１０＾５和５．４２×１０＾４个柔嫩艾美尔球虫孢子化卵囊，第３组对照。结果，第１、２组在感染后第４天呈现血便，第５天发性死亡，其死亡率分别为１３．６％５０和５．４％。尸体剖检，盲肠明显肿大，肠壁出血；后期，盲肠萎缩，并出现干酪样肠 芯。病理组织学变化特点，为出血一坏死性或出血一卡地他性盲肠炎，以及出血一卡他性直肠炎。第８天  相似文献   

Stereotactic radiation therapy for treatment of canine intracranial meningiomas          下载免费PDF全文

L.R. Griffin  M.W. Nolan  L.E. Selmic  E. Randall  J. Custis  S. LaRue 《Veterinary and comparative oncology》2016,14(4):e158-e170

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NTPDase and 5′-nucleotidase as inflammatory markers in cattle naturally infected by Eurytrema coelomaticum     

《Comparative immunology, microbiology and infectious diseases》2016

The aim of this study was to evaluate seric NTPDase and 5′nucleotidase activities of cattle naturally infected by Eurytrema coelomanticum, as well as to correlate them to histopathological lesions in the pancreas and the degree of parasitism. Blood samples and pancreas of 51 bovines were collected on a slaughterhouse in Southern Brazil: 33 from cattle naturally infected by E. coelomanticum (the Group A), and 18 from uninfected animals (the Group B). Infected animals showed an average of 532 parasites per pancreas. In the pancreatic histology, ducts displayed hyperplasia, stenosis, proliferation of fibrous tissue, and interstitial inflammatory infiltration of lymphocytes. The serum from infected animals showed an increase in NTPDase activity when ATP was used as substrate (P < 0.001). For the ADP substrate, there was no difference between groups regarding NTPDase activity (P = 0.37), as well as 5′-nucleotidase activity (P = 0.27). Correlating NTPDase activity (ATP substrate) with the degree of histopathological lesions (rho = 0.66, P < 0.001) and the parasitic load on the pancreas (rho = 0.65, P < 0.001), a positive correlation was observed. Similar results were found between the degree of histopathological lesions and NTPDase activity (ADP substrate; rho = 0.29, P = 0.03), and 5′nucleotidase activity (rho = 0.35, P = 0.01). Based on the results of NTPDase and 5′nucleotidase enzymes in cattle naturally infected by E. coleomanticum, it is possible to suggest that these enzymes are involved in the modulation of inflammation, and they can act as markers of inflammatory response.  相似文献   

Pathological study of dilated cardiomyopathy     

CAO Wen-jun  LI Liang  LIU Guo-zhen  LIN Jie  HUANG Fang-jiong  YANG Pei-sun 《园艺学报》2001,17(8):755-758

AIM: To study the pathological features of the dilated cardiomyopathy and the mechanisms involved. METHODS: The left ventricular myocardium specimens were obtained from 8 patients with dilated cardiomyopathy by BATISTA. The morphological changes was examined macropathologically and histopathologically. RESULTS: The dilated cardiomyopathy from 8 patients can be classified into two types macropathology. One of them showed hypertrophy of left ventricular wall and the other showed fatty infiltration on myocardium of the left ventricular. In the first type, swelling of the endothelial cells as well as luminal stenosis even occlusive of small arteries and arterioles were observed in the study. Electronical microscopical examination showed that there were a lot of homogeneous secretory granules in the endothelial cells. CONCLUSION: These results suggested that the secretory granules might be from the damaged myocardial cells and entered into the adjacent endothelial cells. The pathological changes mentioned above could aggravate the ischemia of myocardium. At the same time, the vicious cycle make the pathological changes more serious. Further study should be made to confirm the nature of the secretory granules.  相似文献   

Ocular Onchocerca infections in two dogs in western United States     

Eberhard ML  Ortega Y  Dial S  Schiller CA  Sears AW  Greiner E 《Veterinary parasitology》2000,90(4):333-338

Two dogs, one from California and one from Arizona, were found to have aberrant infections caused by filarial nematodes of the genus Onchocerca. In both cases, the parasites are localized in or near the eye. In one case the worm was located in the cornea and was surgically removed. In the second case, a very marked granulomatous reaction was induced in the retrobulbar space, mimicking an abscess. This eye was enucleated. The worms in both instances were female, and were gravid, i.e. contained microfilariae in utero, indicating that a male worm(s) had been present and mating had occurred. The exact identity of the species of Onchocerca responsible cannot be determined, although the features observed are most like Onchocerca lienalis of cattle. These cases represent the fourth and fifth such cases reported from the US, and are especially interesting because of the unusual location of the worms, the small number of recognized cases, and the similarity to a recent zoonotic human infection.  相似文献   

山羊毛霉菌病临床与病理学观察     

汪昭贤  谢毓芬  李国勤  秦晟  董庆爱  赵献军  刘斌锋 《畜牧兽医学报》1998,(1)

以１０７个／ｍｌ微小根毛霉（Ｒｈｉｚｏｍｕｃｏｒｐｕｓｉｌｕｓ）孢囊孢子悬液颈静脉接种２月龄山羊,每只５ｍｌ,每日１次,连续３日,经８８ｄ观察３／４只山羊死亡。病羊临床表现精神沉郁,消瘦,体温升高,腹泻,后肢瘫痪,白细胞总数及嗜中性白细胞成倍增加,全血ＧＳＨ－ＰＸ活性降低,Ｓ－ＧＯＴ、Ｓ－ＧＰＴ和ＡＫＰ活性升高,血清胆固醇值上升,但以上各项血液生化指标变化与对照羊相比差异不显著（ｐ＞０．０５）。病理变化为全身扩散性毛霉菌病,其典型病变在肺脏,整个肺脏遍布灰白色圆形小结节。镜险肺结节中心为毛霉菌丝或碎片,周围淋巴细胞、单核细胞包绕。腿肌大部分肌束呈凝固性坏死,周围微血管内形成血栓  相似文献   

肉鸭实验性锰缺乏症及高磷对缺锰影响的病理学研究     

蔡红  冯泽光 《畜牧兽医学报》1997,28(4):342-348

６９只一日龄天府肉鸭随机分为三组，各喂以基础、高磷、对照。试验分为两个阶段，第一阶（０－４周）结束时，每组各留２只鸭继续进行第二阶段（５－２０或２６周）试验。缺锰组第一周开始发病，第二周迅速达到高峰。  相似文献   

提高民族学生正确观察和绘制病理切片实验技能的探索     

喻华英  焦海宏  张志峰 《塔里木大学学报》2009,21(2):115-117

针对我校民族学生汉语水平较低的客观现实,结合病理学课程特点,本人在病理解剖学实践教学活动中,通过多年教学经验的积累,在引导和提高动医专业民族学生认真、客观地观察和绘制病理切片的教学实践活动中取得较满意的教学效果。  相似文献   

犬实验感染CDV的病理学研究     

遇秀玲  田克恭  吴娜  隋丽华  李俊梅  刘永梅  渠川玫 《中国预防兽医学报》1998,(2)

对实验感染犬瘟热病毒的病犬进行了系统的病理学观察，并用酶标ＳＰＡ法对病犬脏器组织中ＣＤＶ抗原进行了定位检查。结果表明，淋巴系统各器官组织是ＣＤＶ急性感染早期首先侵犯的靶器官。脏器组织的病理改变与ＣＤＶ抗原检出呈正相关。脏器组织中包涵体的检出与形态结构具有一定的特征性和示病意义，但采用免疫组化方法检查ＣＤＶ抗原，更具优越性。作者认为，ＣＤＶ９３０３９株和ＣＤＶ９３０４１株是致病力很强的泛嗜性ＣＤＶ。  相似文献