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Seung-Gon Lee Hyeong-Sun Moon Changbaig Hyun 《Journal of veterinary science (Suw?n-si, Korea)》2008,9(2):197-202
Canine heart worm disease is often life-threatening due to its various complications, including right side heart failure, caval syndrome and pulmonary eosinophilic granulomatosis. Several preventive medications and melarsomine have been developed and they are very effective to control heartworm infestation. However, in a case of severe infestation, melarsomine therapy often results in an unfavorable outcome because of the severe immune reaction caused by rapid killing of the adult worm. Surgical removal and an interventional method using flexible alligator forceps have been well described in the literature. Despite the usefulness of mechanical removal using flexible alligator forceps, the methodology still needs to be upgraded for increasing the applicability for treating dogs with severe infestation. We describe herein a newly developed percutaneous removal method for heartworms and this was successfully applied to 4 dogs with severe heartworm infestation. The follow-up studies also showed favorable outcomes with no complications. 相似文献
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Dirofilaria repens—An etiological factor or an incidental finding in cytologic and histopathologic biopsies from dogs 
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下载免费PDF全文 Katarzyna Paździor‐Czapula Iwona Otrocka‐Domagała Patrycja Myrdek Mateusz Mikiewicz Michał Gesek 《Veterinary clinical pathology / American Society for Veterinary Clinical Pathology》2018,47(2):307-311
Dirofilaria repens is an endemic, zoonotic parasite of carnivores, causing subcutaneous dirofilariasis, which is mostly asymptomatic. The aim of this study was to describe 22 cases of canine subcutaneous dirofilariasis. The cytologic and histopathologic samples were collected from dogs, which presented with various clinical signs such as cutaneous/subcutaneous nodules, hydropericardium, ascites, and lymphadenomegaly. The cytologic or histopathologic examination revealed purulent, pyogranulomatous, granulomatous or eosinophilic dermatitis/panniculitis, and the presence of D repens microfilariae or adults. The microfilariae or adults were also found incidentally in neoplastic cutaneous or subcutaneous tumors and in a sialocele. For the first time, microfilariae were also detected and described in pericardial and abdominal effusions and in enlarged reactive lymph nodes. Although it is well known that D repens can cause dermatitis and panniculitis in dogs, no previous reports of D repens microfilariae in body cavity fluids were found. The role of this parasite in the accumulation of body cavity fluid or in reactive lymphadenomegaly requires further investigation. Due to its zoonotic potential, and apparently underestimated pathogenicity, each case of canine subcutaneous dirofilariasis should be treated. 相似文献
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CANINE DIROFILARIASIS: ITS RADIOGRAPHIC APPEARANCE 总被引：1，自引：0，他引：1
Carol H. Carlisle 《Veterinary radiology & ultrasound》1980,21(3):123-130
Radiography was a valuable aid in the diagnosis of dirofilariasis, even in moderate stages, when the lesions associated with this disease were known and recognized. Pulmonary parenchymal changes is dirofilariasis were more severe around the branches of the pulmonary arteries and, together with the arterial changes, produced a radiographic picture that was characteristic of heartworm disease. These parenchymal changes were classified into alveolar, interstitial, bronchovascular, and mixed patterns. The complexity of the pathologic changes resulted in the radiographic predominance of mixed patterns. The alveolar and mixed patterns produced dense radeiopacities that often masked the arterial detail but regressed with treatment. The interstitial pattern was less dense but usually remained in spite of treatment. Radiographs of dog lungs with dirofilariasis are necessary to initiate a treatment program, as the selection of a particular program depends on the degree of the involvement of the sdpulmonary parenchyma. Adult worms should not be destroyed while severe parenchymal changes persist. A detailed examination of survey radiographs with careful evaluation of pathologic changes involving the lungs, particularly surrounding the main pulmonary artery and its branches, can lead to a diagnosis of dirofilariasis, aid in assessment of the severity of the disease, and assist in planning a treatment program. 相似文献
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Harvey JW Henderson CW French TW Meyer DJ 《Veterinary clinical pathology / American Society for Veterinary Clinical Pathology》1982,11(1):5-11
A 7-year-old male German Shepherd dog with a history of lethargy, weight loss and severe anemia was referred to the University of Florida Veterinary Medical Teaching Hospital for examination. Abnormal laboratory findings included a normocytic and normochromic anemia, thrombocytosis, eosinophilia, basophilia and hyperproteinemia. An increased pulmonary density in the caudal lung lobes was observed on thoracic radiographs. Bone marrow aspiration and core biopsy revealed a hypercellular bone marrow with increased numbers of unidentified blast cells and bizarre megakaryocyte proliferation. Circulating microfilariae were not present in the blood, but serum examined by immunofluorescence was strongly positive for antibodies against Dirofilaria immitis microfilariae. A diagnosis of myeloproliferative disease with megakaryocytic predominance and occult dirofilariasis was made. 相似文献
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Buffy coat smear or Knott's test: which to choose for canine microfilaria screening in field studies? 下载免费PDF全文
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GABRIELA S. SEILER THOMAS J. NOLAN ELEANOR WITHNALL CARYN REYNOLDS JAMES B. LOK MEG M. SLEEPER 《Veterinary radiology & ultrasound》2010,51(2):136-140
Evolution of pulmonary arterial and parenchymal changes as assessed with computed tomography (CT) is described in a dog experimentally infected with Dirofilaria immitis. The dog was imaged 125, 168, 216, and 402 days after infection. Initial changes during the prepatent phase of infection included enlargement of the peripheral caudal lobar pulmonary arteries and intermittent periarterial interstitial infiltrates. The changes were progressive, involving additional arteries over time, but remained mild. With the presence of adult filariae a filling defect was observed in the caudal lobar pulmonary artery using CT angiography. Recognizing thoracic CT findings associated with the prepatent phase of canine heartworm infection may be important in endemic areas. 相似文献
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Prasit Supakorndej PhD Robert E. Lewis DVM MS John W. McCall PhD Michael T. Dzimianski MS DVM Robert A. Holmes DVM PhD 《Veterinary radiology & ultrasound》1995,36(1):23-29
Five ferrets of each sex were each inoculated with 15 third-stage infective larvae of Dirofilaria immitis to study radiographic and angiographic changes in the cardiopulmonary system following heartworm infection; 5 additional ferrets of each sex served as noninfected controls. Prior to inoculation and every 8 weeks thereafter until 40 weeks, the infected and noninfected ferrets were radiographed; angiographic examinations were done prior to necropsy. At necropsy, the worms in the heart, lungs, and associated vessels were counted, and lung histosections were prepared and examined for changes. Radiographic changes were seen in the right side of the heart and associated vessels of infected ferrets as compared with the noninfected ferrets, but changes were less prominent than those seen in heartworm-infected dogs and cats. The changes were primarily an increase in the size of the right side of the heart, especially the right atrium. Radiographically, no changes could be visualized in the pulmonary vascular system. Worms in the enlarged cranial vena cava, azygous vein, and left caudal lobar pulmonary artery of infected animals were delineated by angiography. Histologically, no changes were seen in the pulmonary vascular tissues. 相似文献
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