FoxA2 and p53 regulate the transcription of HSD17B1 in ovarian granulosa cells of pigs     

Xiaolong Yuan  Xiaofeng Zhou  Xiwu Qiao  Qi Wu  Zhixiang Yao  Yao Jiang  Hao Zhang  Zhe Zhang  Xilong Wang  Jiaqi Li 《Reproduction in domestic animals》2021,56(1):74-82

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藏绵羊卵巢组织学及卵泡超微形态的观察     

郭亚军  柳苗苗  付德海  冉兴荣  王欣荣 《畜牧兽医学报》2021,52(2):389-398

旨在通过观察藏绵羊卵泡、黄体的组织学特征及卵泡的超微形态,探讨其与生理功能的关系。本研究运用大体解剖、常规组织切片和H.E染色及透射电镜技术对藏绵羊卵巢卵泡和黄体的组织结构特点以及卵泡的超微形态进行观察和分析。结果发现,藏绵羊黄体期和卵泡期卵巢的宽度和厚度存在显著差异（P<0.05）,而重量和长度无显著差异（P>0.05）;卵巢上的大多数卵泡通过颗粒细胞萎缩和纤维化而闭锁;黄体中膜黄体细胞（直径22 μm）和颗粒黄体细胞（直径50 μm）结构特征明显且分界清晰,其内部分布着丰富的毛细血管;通过观察卵泡的超微形态发现,随着卵泡的发育,卵泡细胞的形状由椭圆形变为多边形,数量增多且被膜细胞包围;细胞器数量和种类也增多且之间联系紧密,胞质可见分泌的皮质颗粒。结果表明,藏绵羊卵泡系统和黄体的组织学特点以及卵泡的超微形态与其他绵、山羊类似,随着卵泡的发育,血管增生较快,卵泡结构特征变化明显和细胞器致密化程度增加且卵泡在不同时期均会闭锁;黄体内部在毛细血管滋生下使两种黄体细胞结构更加完整且特征明显,这可能是藏绵羊在高原低氧环境下仍然能够发挥卵巢机能的重要基础保障。  相似文献   

Altered vitamin D metabolic system in follicular cysts of sows     

Malgorzata Grzesiak  Magdalena Socha  Anna Hrabia 《Reproduction in domestic animals》2021,56(1):193-196

This study aimed to examine 25OHD₃ concentration in the fluid of follicular and follicular lutein cysts of sows in comparison with preovulatory follicles as well as immunolocalize vitamin D metabolic enzymes (CYP27B1 and CYP24A1) and determine their protein abundances in the cyst wall. We have shown for the first time that 25OHD₃ level in the fluid of both cyst types was significantly lower than in preovulatory follicles. Furthermore, we have demonstrated CYP27B1 and CYP24A1 protein immunolocalization and abundance in follicular and follicular lutein cysts. The abundance of protein for both metabolic enzymes was decreased in ovarian cysts when compared to preovulatory follicles. We propose that altered VD metabolism in ovarian cyst might associate with their formation in sows.  相似文献   

Kisspeptin-10对蛋鹌鹑卵巢发育与内分泌的影响     

钱福玉  史盈频  裴静  骆海波  黄炎冰  倪迎冬 《畜牧与兽医》2012,44(10)

为研究Kisspeptin-10(Kp-10)对禽类生殖内分泌的影响,将75羽22日龄雌鹌鹑随机分为3组,分别腹腔注射300μL生理盐水(对照组),注射0.1 nmol Kp-10(低剂量组)和1 nmol Kp-10(高剂量组),每日注射1次,连续注射3周。记录鹌鹑开产情况,并于60日龄时采集血液和卵泡组织,测定生殖激素与受体的mRNA表达。结果:与对照组相比,注射Kp-10组鹌鹑产蛋率显著提高,且大卵泡数显著增加,血液中雌激素水平显著升高;低剂量组输卵管重显著增加,但体重、肝脏重和小卵泡重无显著变化。Real-time PCR结果显示,Kp-10处理显著下调小卵泡及F1级卵泡上促黄体激素受体(LHR)、促卵泡激素受体(FSHR)和促性腺激素释放激素Ⅰ(GnRH-Ⅰ)的基因表达。  相似文献   

应用Ovsynch技术促进奶牛产后卵巢周期活动恢复的研究     

何举  杨延周  史远刚 《安徽农业科学》2010,38(2):744-745

[目的]确定奶牛产后卵巢周期活动恢复的最佳方案。[方法]应用诱导促排卵（Ovsynch）技术GnRH＋PG、GnRH＋CIDR＋PG及2次PG方法对产后20·d体况评分为2．75～3．50、子宫复1日较好、卵巢无明显卵泡和黄体活动的奶牛进行处理，比较不同处理奶牛产后卵巢开始活动的时间、产后第1次发情时间、产后第1次配种时间、空胎天数等。[结果]GnRH＋CIDR＋PG及2次PG处理可显著缩短奶牛产后卵巢开始活动的时间、产后第1次配种时间和空胎天数；3个处理奶牛产后第1次发情时间无显著差异。[结论]GnRH＋CIDR＋PG及2次PG处理对奶牛产后卵巢周期活动恢复具有明显的促进作用。  相似文献   

Dermatophyte granulomas caused by Trichophyton mentagrophytes in a dog     

Bergman RL  Medleau L  Hnilica K  Howerth E 《Veterinary dermatology》2002,13(1):49-52

Multiple, dermal and subcutaneous nodules developed in a young female Manchester Terrier dog that had a chronic history of superficial dermatophytosis. Skin biopsy specimens of the nodules revealed granulomatous inflammation in the deep dermis and subcutis with branching fungal organisms. Cultures of multiple biopsy specimens from the nodules all yielded Trichophyton mentagrophytes. The lesions in this dog were similar to granulomatous dermatophytosis, a skin disease that has been reported in Persian cats and one Yorkshire Terrier dog.  相似文献   

腹腔镜下输卵管切除术对卵巢功能的近期影响     

方光光  刘志恒陈虹 高素清 《长江大学学报》2007,4(2):150-151

目的：探讨腹腔镜下输卵管切除术对卵巢功能的近期影响。方法：将60例拟行输卵管切除术的异位妊娠患者随机分为3组（n=20）．手术方式分别采用腹腔镜单极电凝．腹腔镜双极电凝和开腹手术。术后1月、3月检测血清E2、P、T、FSH和LH水平，并与20例健康志愿者的激素水平相比较，观察患者术后月经恢复情况。结果：3组病人手术后卵巢激素水平与健康志愿者无显著差异，各组之间亦无显著差异，术后月经恢复情况各组之间也无明显差异。结论：与开腹手术一样．腹腔镜输卵管切除术对卵巢功能无明显影响。  相似文献   

恒河猴(M.mulatta)肝囊原虫病的研究——Ⅱ.病理学观察     

林在尧 《扬州大学学报(农业与生命科学版)》1986,(3)

对恒河猴(M.mulatta)肝囊原虫病的病理变化进行了系统观察与描述,发现除肝脏囊样病灶与炎性浸润外,尚有不同程度的肝外器官损害,其中一例首次查出肺部迷路寄生。另外,作者还对本病的发病机制作出初步讨论。  相似文献   

Luteoma in two mares treated by ovariectomy     

E. Combs  T. Beachler  J. R. Troy  A. Olds-Sanchez  J. M. Howard  A. Fales-Williams  M. Yaeger  D. M. Tatarniuk 《Equine Veterinary Education》2022,34(8):e318-e322

A 15-year-old Paint mare (Case 1) and a 15-year-old Arabian mare (Case 2) were presented for aggressive and undesired behaviour. Reproductive evaluation revealed, initially, an enlarged ovary with a smaller/normal sized contralateral ovary in each case. Granulosa cell tumour (GCT) panel testing revealed elevated inhibin B in both cases and elevated anti-Mullerian hormone (AMH) levels only in Case 1 determined from currently established reference ranges. Based on a presumptive diagnosis of GCT, bilateral standing ovariectomy was elected for both mares. In each case neoplastic tissue consistent with luteoma was detected only on histological examination in the smaller/normal sized left ovary; the right ovary appearing normal. Long-term follow-up was performed 1 year and 5 years post-operatively by telephone. The owners were satisfied with the outcome and each patient demonstrated resolution of aggressive stallion-like behaviour. Each case returned to the owners' intended use. In conclusion, luteoma should be considered as a differential diagnosis for ovarian neoplasms in horses related to behavioural abnormalities, even in normal-sized ovaries.  相似文献   

A review of oestrus suppression techniques in mares     

J. R. Crabtree 《Equine Veterinary Education》2022,34(3):141-151

Many fillies and mares are accused of behaving badly by their owners or trainers, and their reproductive hormones and ovaries are commonly blamed for this. Overt oestrus behaviour, however natural, is undesirable when a horse is being ridden, trained and competed. More subtle behaviours may be attributed to the reproductive cycle and presented as the cause of poor performance in the elite competition mare. Sometimes behaviours are complex, perhaps at odds with what one expects for normal reproductive behaviour and in many cases may not be associated with the reproductive cycle at all, rather associated with pain of musculoskeletal or soft tissue origin. The situation represents a diagnostic dilemma to positively associate undesirable behaviours with the ovarian hormones or ovarian pain, before an attempt can be made to modify the behaviour through the suppression of oestrus. This article will review the reasons for presentation, the behavioural patterns of the reproductive cycle and the diagnosis of reproductive behavioural problems. The range of techniques for oestrus suppression will be reviewed along with their clinical application and any known current regulatory issues associated with their use.  相似文献