全沟硬蜱围食膜初步观察研究     

朱振勤  夏明仪  陈季武  夏晶  傅蓓蓓 《中国兽医寄生虫病》2002,10(4):1-4

本工作用光镜和电镜技术对全沟硬蜱的围食膜进行了初步观察研究。结果表明，饥饿幼虫、若虫、成虫以及吸血期雄性成虫不具围食膜。吸血期幼虫、若虫及雌性成虫最晚分别于吸血开始后20、20及18小时出现了单层结构的围食膜；缓慢吸血期围食膜的厚度持续增加，而在快速吸血期其厚度却会显著减小。饱血后发育期围食膜不断增厚，愈来愈拱曲，与肠壁的距离不断扩大，并形成多层结构；至少分别于饱血后12、25及11天，仍能在幼虫、若虫及雌性成虫肠腔观察到完好状态的围食膜。全沟硬蜱是我国北方地区多种血液传播病原体的重要媒介，其围食膜的发现及围食膜形态变化的初步描述，对进一步认识这些病原体在全沟硬蜱体内迁移扩散规律、发育动态以及向宿主的传播途径，可提供有益的启示。  相似文献   

永靖县羊血液原虫病综合防治试验   总被引：1，自引：1，他引：0  

吴志仓 《中国兽医寄生虫病》2003,11(1):8-11

1999-2001年，在永靖县羊血液原虫病流行区进行了最佳灭蜱药物筛选试验和抗原虫药物预防、治疗羊泰勒虫病效果对比观察试验。结果表明：最佳灭蜱药物是灭蜱灵，平均有效期为55d，灭蜱预防后的发病率可降低到3.07％；虫克星是理想的防治辅助用药；贝尼尔脂质体和贝尼尔与蜱灵配合应用后，预防保护期达54d、45d，用药后60d发病率为2％、2.27％，比对照组49.46％降低47.46、47.19个百分点，预防效果明显；贝尼尔脂质体和焦虫净的治愈率为95％、87.85％，比对照组35.71％提高59.29、52.14个百分点，是首选治疗药物。  相似文献   

蜱传性疾病--莱姆病螺旋体研究进展   总被引：6，自引：0，他引：6  

廖德丰  陈季武  谢萍  傅蓓蓓  朱振勤 《中国兽医寄生虫病》2004,12(2):36-39

莱姆病是一种蜱传性人兽共患病,在我国北方各省广泛流行,其病原体为伯氏疏螺旋体。莱姆病可使皮肤、心脏、关节和神经系统等多种组织器官受损。本文综述了莱姆病螺旋体的形态、种下分类、生化特征、传播媒介和贮存宿主等方面的研究进展"  相似文献   

Detection of Invasive Borrelia burgdorferi Strains in North‐Eastern Piedmont,Italy          下载免费PDF全文

M. D. Pintore  L. Ceballos  B. Iulini  L. Tomassone  A. Pautasso  D. Corbellini  F. Rizzo  M. L. Mandola  M. Bardelli  S. Peletto  P. L. Acutis  A. Mannelli  C. Casalone 《Zoonoses and public health》2015,62(5):365-374

Following reports of human cases of Lyme borreliosis from the Ossola Valley, a mountainous area of Piemonte, north‐western Italy, the abundance and altitudinal distribution of ticks, and infection of these vectors with Borrelia burgdorferi sensu lato were evaluated. A total of 1662 host‐seeking Ixodes ricinus were collected by dragging from April to September 2011 at locations between 400 and 1450 m above sea level. Additional 104 I. ricinus were collected from 35 hunted wild animals (4 chamois, 8 roe deer, 23 red deer). Tick density, expressed as the number of ticks per 100 m², resulted highly variable among different areas, ranging from 0 to 105 larvae and from 0 to 22 nymphs. A sample of 352 ticks (327 from dragging and 25 from wild animals) was screened by a PCR assay targeting a fragment of the 16S rRNA gene of B. burgdorferi s.l. Positive samples were confirmed with a PCR assay specific for the 5S‐23S rRNA intergenic spacer region and sequenced. Four genospecies were found: B. afzelii (prevalence 4.0%), B. lusitaniae (4.0%), B. garinii (1.5%) and B. valaisiana (0.3%). Phylogenetic analysis based on the ospC gene showed that most of the Borrelia strains from pathogenic genospecies had the potential for human infection and for invasion of secondary body sites.  相似文献   

蜱免疫球蛋白结合蛋白研究进展     

万修红  周金林 《中国兽医寄生虫病》2006,14(4):42-45

蜱体内的免疫球蛋白结合蛋白（immunoglobulin binding protein，IGBP）主要存在于血淋巴和唾液腺中，可以与进入蜱血淋巴中的宿主免疫球蛋白（immunoglobulin，Ig）结合，从而避免宿主免疫球蛋白对蜱内部器官的损害。免疫球蛋白结合蛋白结构和功能的进一步阐明，可为抗蜱疫苗的研发提供新的思路。本文综述了免疫球蛋白结合蛋白的发现及其研究进展。  相似文献   

The Effects of Salivary Gland Extracts from <Emphasis Type="Italic">Boophilus microplus</Emphasis> Ticks on Mitogen-stimulated Bovine Lymphocytes     

Turni C  Lee RP  Jackson LA 《Veterinary research communications》2007,31(5):545-552

The effect of salivary gland extract (SGE) from the tick Boophilus microplus was examined in mitogen-stimulated lymphocytes in vitro. SGE was added to lymphocytes of seven cattle together with the mitogens concanavalin A (ConA), phytohaemagglutinin (PHA) and pokeweed mitogen (PWM). Semi-purified B cells from another seven cattle were stimulated with the mitogen lipopolysaccharide (LPS). PHA and ConA stimulated proliferation of lymphocytes to the same extent, but the inhibition due to SGE of Boophilus microplus on the proliferative response stimulated by PHA (39.0% ± 9.3%) was less than the inhibition of proliferative response stimulated by ConA (75.4% ± 6.9%). In contrast, SGE of B. microplus stimulated the proliferation of B cells in the presence of LPS in a dose-dependent manner. Enhanced stimulation of B cells by SGE at >4 μg in culture was greater than twice that observed when B cells were stimulated by LPS alone. SGE does not have a direct suppressive effect on bovine B cell proliferation; however, in vivo the effectiveness of B cell responses might be influenced by other immune factors, such as cytokine profiles.  相似文献   

牛羊梨形虫病及媒介蜱综合防治药物筛选          下载免费PDF全文

赵延红 《中国牛业科学》2023,49(4):32-35

天祝县莫客片一带牛梨形虫病发病率达24.6%,病死率28.6%;羊发病率34.2%,病死率27.5%,与往年相比变化不大,笔者从蜱控制、梨形虫病预防加治疗相结合综合防控入手,作控制、预防药物试验对比,筛选药效长、低毒、安全、广谱药物,结果显示用敌杀死环境灭蜱,同时注施可诺注射液控制蜱感染,用蒿甲醚注射液或盐酸咪唑苯脲,预防和治疗梨形虫病,能有效降低当地牛羊梨形虫病的发病率和病死率。  相似文献   

Confirmed Exposure to Tick‐Borne Encephalitis Virus and Probable Human Cases of Tick‐Borne Encephalitis in Central/Northern Anatolia,Turkey     

K. Ergünay  M. B. Saygan  S. Aydoğan  N. Litzba  B. Şener  S. Lederer  M. Niedrig  G. Hasçelik  D. Us 《Zoonoses and public health》2011,58(3):220-227

Tick‐borne encephalitis virus (TBEV) is the aetiological agent of tick‐borne encephalitis (TBE), a potentially fatal central nervous system infection of humans. TBE is endemic in many areas of Europe and Asia; however, very scarce data on TBEV activity are available from Turkey. We aimed to identify TBEV exposure in healthy blood donors and the impact of TBEV in central nervous system infections in Central/Northern Anatolia. Two‐thousand four hundred and fifty four sera, collected from blood donors at Ankara, Konya, Eski?ehir and Zonguldak branches of the Turkish Red Crescent Middle Anatolia Regional Blood Center, were analysed for TBEV serosurveillance. Paired serum and cerebrospinal fluid samples from 108 patients with the diagnosis of aseptic meningitis/encephalitis of unknown aetiology were also evaluated to identify TBE and neuroborreliosis cases. Commercial enzyme‐linked immunosorbent assays and indirect immunofluorescence tests were employed for antibody detection. Forty‐seven donor samples (1.9%) were reactive for TBEV IgG. In 25 persons with IgG reactivity (53.1%), risk factors for tick‐borne infections were revealed. One sample from Zonguldak province (1/198; 0.5%) in the Black Sea region of Turkey was confirmed to possess neutralizing antibodies via plaque reduction neutralization test. TBEV IgM was detected in 9.2% (8/108) of the patients. IgM was accompanied by IgG reactivity in two persons where, in one, recent history of a tick bite was also identified. Intrathecal antibody production for TBEV could not be demonstrated. No evidence for Borrelia infections could be found. Confirmed exposure to TBEV and/or an antigenically similar tick‐borne flavivirus is documented for the first time in blood donors in Zonguldak in Northern Anatolia. Probable cases of TBE have also been identified from Central Anatolia. The epidemiology of TBEV activity in Turkey needs to be assessed and benefits of vaccination for general population, risk groups or travellers must be considered.  相似文献   

新疆喀什市周边地区绵羊寄生蜱种类调查   总被引：1，自引：0，他引：1  

廖秋萍  王时伟 《塔里木大学学报》2005,17(4):42-43

2005年4月下旬，我们对喀什市周边地区绵羊寄生蜱种类进行了调查。鉴定出2个科11个属的17种蜱，其中有3属未做种的鉴定。  相似文献   

Retrospective study of 103 presumed cases of tick (Ixodes holocyclus) envenomation in the horse     

Ruppin M  Sullivan S  Condon F  Perkins N  Lee L  Jeffcott LB  Dart AJ 《Australian veterinary journal》2012,90(5):175-180

Objective Review 103 cases of presumed tick envenomation in horses. Design Retrospective study. Method Variables, including date of presentation, age, breed, weight, presence of ticks, gait and respiration scores, duration of recumbency, treatment, outcome and complications were recorded. A series of univariable screening tests were performed and used in a multivariable logistic regression model. Results There were a total of 103 cases affecting 10 breeds, aged between 1 week and 18 years of age. Horses >6 months old and weighing >100 kg had a higher odds of death than those <6 months old and <100 kg. Cases were seen from North Queensland to the central coast of New South Wales and were more likely to present in the warmer months. There was no association between the number of ticks found on an animal and death. Horses with a higher respiratory score had higher odds of dying, but there was no association between gait score and survival. Horses recumbent >120 h after presentation had higher odds of dying. Complications were reported in 35% of horses. The odds ratio for survival was higher for horses receiving >0.5 mL/kg of tick antiserum. Overall, 74% of horses survived. Multivariable modelling was limited by the small sample size. Conclusion In general, tick envenomation in horses follows the geographic distribution of Ixodes holocyclus. Tick antiserum administered at >0.5 mL/kg increases the odds of survival. It would appear that the complications associated with managing a recumbent horse increase the odds of death.  相似文献