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排序方式： 共有358条查询结果，搜索用时 15 毫秒
1.
内毒素介导动物急性肾功能衰竭机理的试验研究 总被引：2，自引：0，他引：2
为了阐明内毒素介导急性肾功能衰竭的机理,观察了内毒素性肾功能衰竭家兔血液凝固性变化和肾脏的病理形态学变化。与对照组家兔比较,模型组家兔血小板计数和血浆纤维蛋白原含量极显著降低(P<0 01),出血时间、凝血时间、凝血酶原时间和白陶土部分凝血活酶生成时间显著或极显著延长(P<0 05,P<0 01)。另一方面,内毒素注射在全部模型组家兔导致了弥漫性血管内凝血,71.4%的肾小球中发现了微血栓,肾小球纤维素密度指数达60 6%。此外,96.2%的肾小管上皮细胞变性坏死,84.1%的肾小管中有管型形成。对照组家兔均未发现这些病理变化。上述试验结果揭示,内毒素引发了弥漫性血管内凝血,而肾小球毛细血管内广泛形成的微血栓阻断了肾小球毛细血管血流,从而导致肾小球滤过率降低,这是内毒素介导急性肾功能衰竭的首要机理。此外,肾小管上皮细胞的变性、坏死可损害其重吸收和分泌功能,管型形成可阻塞肾小管管腔并增大肾球囊内的压力,这些也都是在内毒素介导急性肾功能衰竭发生发展过程中起重要作用的因素。 相似文献
2.
Specific ion effects (Hofmeister effects) have recently attracted the attention of soil scientists, and it has been found that ionic non-classic polarization plays an important role in the specific ion effect in soil. However, this explanation cannot be applied to H+. The aim of this work was to characterize the specific ion effect of H+ on variably charged soil (yellow soil) colloid aggregation. The total average aggregation (TAA) rate, critical coagulation concentration (CCC), activation energy, and zeta potential were used to characterize and compare the specific ion effects of H+, K+, and Na+. Results showed that strong specific ion effects of H+, K+, and Na+ existed in variably charged soil colloid aggregation. The TAA rate, CCC, and activation energy were sensitive to H+, and the addition of a small amount of H+ changed the TAA rate, CCC, and activation energy markedly. The zeta potential results indicated that the specific ion effects of H+, K+, and Na+ on soil colloid aggregation were caused by the specific ion effects of H+, K+, and Na+ on the soil electric field strength. In addition, the origin of the specific ion effect for H+ was its chemical adsorption onto surfaces, while those for alkali cations were non-classic polarization. This study indicated that H+, which occurs naturally in variably charged soils, will dominate variably charged soil colloid aggregation. 相似文献
3.
4.
Differentiation between dogs with thrombosis and normal dogs using the overall hemostasis potential assay 
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下载免费PDF全文 Anna L. Dengate BVSc BMedSc Marie‐Christine Morel‐Kopp PhD Julia A. Beatty PhD BVetMed BSc Vanessa Barrs BVSc MVetClinStud Jody A. Braddock BVSc MVetClinStud Richard K. Churcher BVSc Bethany J. Wilson BVSc PhD Christopher M. Ward BMedSc MBChB PhD 《Journal of Veterinary Emergency and Critical Care》2016,26(3):446-452
5.
Thromboelastographic assessment of the contribution of platelets and clotting proteases to the hypercoagulable state of dogs with immune‐mediated hemolytic anemia 下载免费PDF全文
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7.
M. Ryan Smith DVM DACVECC Virginie A. Wurlod MS Dr vet med DACVECC DECVECC Chin-Chi Liu MS MApStat PhD 《Journal of Veterinary Emergency and Critical Care》2023,33(6):648-655
Objective
To describe hemostatic derangements associated with canine anaphylaxis and to assess for association with syndrome severity.Design
Prospective observational study.Setting
University teaching hospital.Animals
Twenty-seven client-owned dogs, recruited from November 2018 to January 2022, diagnosed with anaphylaxis of varying severity were included. Study inclusion required presentation <6 hours after initiation of clinical signs, no medications or history of illness within the prior 2 weeks, lack of comorbidities expected to affect hemostasis, and lack of a disease state that could alternatively explain the clinical presentation.Interventions
Blood samples were collected within the first hour of presentation for CBC, serum biochemistry, prothrombin time (PT), activated partial thromboplastin time (aPTT), and viscoelastic coagulation testing for use with a cartridge-based point-of-care device.Measurements and main results
Clotting time and clot formation time were prolonged, alpha angle and maximum clot firmness were decreased, PT and aPTT were prolonged, and platelet counts were lower in severe cases compared to mild and moderate cases. There were no differences for any parameter between mild and moderate cases. The presence or absence of abdominal effusion was not associated with hemostatic status.Conclusions
Global hemostatic derangements consistent with hypocoagulability are a prominent feature of severe anaphylaxis in dogs and should be considered for routine evaluation. 相似文献8.
9.
静电凝并中荷电粒子的运动方程及近似解 总被引：2，自引：0，他引：2
本文分析静电除尘器预凝并粒子的运动情况,研究了荷电气固两相流中粒子运动与气流运动的关系,通过对荷电粒子的受力分析,在粒子运动过程中考虑了库仑力、压差力、附加质量力、Stokes阻力以及Basset力对荷电粒子的作用,而忽略其它力的影响,建立了湍流中描述粒子运动的基本方程—BBO(Basset-Boussinesq-Oseen)方程,用谱分解方法进行求解,并得到荷电粒子凝并运动方程的两组近似解,从而确定了粒子运动与气流运动的关系,αr为近似解的重要参数,随着αr的变化,粒子运动的复杂性随之变化。 相似文献
10.