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排序方式: 共有353条查询结果,搜索用时 15 毫秒
1.
对自然铅镉中毒绵羊骨骼损伤的X线特征及骨组织重金属元素的沉积进行了系统研究。结果表明,由于重金属元素在骨骼中的高度蓄积,致使骨中Ca,P代谢紊乱,重金属中毒呈现以骨质疏松为特征的骨营养不良。头颅、胸部及四肢X线摄影检查显示,病羊骨骼主要病理变化是普遍性骨质疏松,牙齿磨灭不齐,四肢长骨密度减低,骨皮质变薄,骨髓腔增宽,骨小梁稀少,骨指数显著低于健康羊(P<0.05)。 相似文献
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To study the effect of luteolin on blood indexes,liver and kidney in mice with acute mercury poisoning,28 mice were randomly divided into four groups:Control group (intraperitoneal injection 0.9% saline),luteolin group (lavage 100 mg/kg luteolin),mercuric chloride group (intraperitoneal injection 4 mg/kg mercury chloride) and mercury chloride+luteolin group (intraperitoneal injection 4 mg/kg mercuric chloride,lavage 100 mg/kg luteolin).The activities of ALT in serum,AST,CREA and BUN contents,blood WBC,RBC,HGB content and GSH and MDA contents of liver tissue were detected.Morphological changes of liver and kidney tissues were observed.The results showed that compared with the control group,the activities of ALT and AST of mercuric chloride group were extremely significantly increased (P < 0.01),serum CREA,BUN,blood WBC and liver tissue MDA contents were significantly increased (P < 0.05) while blood RBC,HGB and liver tissue GSH contents were significantly decreased (P < 0.05).Liver,kidney pathological changes were obviously.Compared with mercuric chloride group,the activities of ALT,AST in serum,CREA,BUN,blood WBC and liver tissue MDA contents of mercuric chloride+luteolin group were significantly decreased (P < 0.05),while blood RBC,HGB and liver tissue GSH contents were significantly elevated (P < 0.05).Liver,kidney pathological changes were attenuated obviously.The poisoning were characterized by inflammation and the occurrence of anemia when acute mercury poisoning occurred,liver and kidney showed different degrees of injury in mice.Luteolin could reduce the toxic effects of acute mercury poisoning on blood,liver and kidney. 相似文献
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用三氮脒以3.5 mg/kg的剂量对患有附红细胞体病的藏獒进行肌肉注射,隔日用同等剂量的三氮脒肌肉注射,24 h后,藏獒发生以神经症状为主的中毒现象,并表现出食欲废绝,后肢发软,四肢抽搐呈划水状,卧地不起,昏迷,体温正常临床症状。经血清生化检验,藏獒的尿素氮、肌酸激酶等的生化指标明显升高,血糖降低占病例的100%。经过5 d的药物治疗后,中毒藏獒基本恢复健康。 相似文献
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A review of cyanobacterial odorous and bioactive metabolites: Impacts and management alternatives in aquaculture 总被引:2,自引:0,他引:2
Juliette L. Smith Greg L. Boyer Paul V. Zimba 《Aquaculture (Amsterdam, Netherlands)》2008,280(1-4):5-20
Increased demand has pushed extensive aquaculture towards intensively operated production systems, commonly resulting in eutrophic conditions and cyanobacterial blooms. This review summarizes those cyanobacterial secondary metabolites that can cause undesirable tastes and odors (odorous metabolites) or are biochemically active (bioactive metabolites) in marine and freshwater, extensive and intensive aquaculture systems. For the scope of this paper, biochemically active metabolites include (1) toxins that can cause mortality in aquaculture organisms or have the potential to harm consumers via accumulation in the product (hepatotoxins, cytotoxins, neurotoxins, dermatoxins, and brine shrimp/molluskal toxins), (2) metabolites that may degrade the nutritional status of aquaculture species (inhibitors of proteases and grazer deterrents) or (3) metabolites that have the potential to negatively affect the general health of aquaculture species or aquaculture laborers (dermatoxins, irritant toxins, hepatotoxins, cytotoxins). Suggestions are made as to future management practices in intensive and extensive aquaculture and the potential exposure pathways to aquaculture species and human consumers are identified. 相似文献
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ABSTRACT: The toxic dinoflagellates Alexandrium tamarense (Lebour) Balech and A. catenella (Whedon and Kofoid) Balech produce potent neurotoxins, such as saxitoxin and gonyautoxin and have been mainly responsible for paralytic shellfish poisoning (PSP) in Japan. To prevent a negative effect on the fishery industry, it is necessary to identify these toxic species precisely and rapidly before and during the bloom. In this paper, a rapid and simple protocol of a fluorescence in situ hybridization (FISH) method using ribosomal RNA (rRNA)-targeted probes has been established for identifying the cultured strains and natural cells of A. tamarense and A. catenella . Using the FISH method established in this study, it was possible to identify these toxic species species-specifically and rapidly, within 30 min. The procedure of detection constituted three steps: (i) fixation/dehydration; (ii) hybridization; and (iii) washing; this made the identification simple. Moreover, this method did not require either special techniques or equipment, and the cost for detection was low. The specificity, rapidity, and simplicity of the developed method suggest that it might be useful for routine monitoring of these toxic microalgae. 相似文献
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山羊冰川棘豆中毒的血液学指标分析 总被引:1,自引:0,他引:1
10只杂种奶山羊随机等分为试验组和对照组 ,试验组羊按 10 g/ ( kg· d)的剂量饲喂冰川棘豆干粉 ,定期采血 ,进行血液 RBC、Hb、PCV、WBC、白细胞分类记数和全血淋巴细胞空泡变性的测定 ,并计算 MCH、MCV、MCHC。结果表明 ,RBC、Hb、PCV、MCH、MCV、MCHC明显低于对照组 ,与对照组比较差异极显著 ( P<0 .0 1) ,淋巴细胞出现空泡变性 ,中毒羊造血系统受到损害 ,抵抗力降低 ,贫血属小细胞性贫血 相似文献
10.
棘豆属植物及其有毒成分的中毒病理学研究 总被引:6,自引:0,他引:6
对棘豆属植物中的生物碱提取、分离和鉴定后,证实生物碱中含有苦马豆素。通过对两组小白鼠分别饲添加棘豆属植物粉和生物碱的中毒实验,发现两组小白鼠都发生中毒,其临床症状,剖检变化,病理组织变化基本相同,表明生物碱是棘豆属植物中主要毒性成分,实验除采用常规H.E染色外,还应用组织化学和透射电镜等检测手段,较细致地观察了小白鼠束棘豆中毒后的病理变化。 相似文献