MENSURATION OF THE NORMAL PITUITARY GLAND FROM MAGNETIC RESONANCE IMAGES IN 96 DOGS     

Hege  Kippenes  DVM  Patrick R.  Gavin  DVM  PhD  Susan L.  Kraft  DVM  PhD  Ronald D.  Sande  DVM  MS  PhD  Russell L.  Tucker  DVM 《Veterinary radiology & ultrasound》2001,42(2):130-133

The pituitary gland was measured from transverse magnetic resonance T1-weighted images after Gadolinium administration in 96 dogs weighing from 13 to 45 kg. The measurements were done by hand with calipers. The mean (+/- standard deviation) pituitary gland height was 5.1 mm (+/-0.9 mm). The mean width was 6.4 mm (+/- 1.1 mm). The correlation coefficient between pituitary and brain measurements, between pituitary measurement and body weight, and brain measurements and body weight was 0.0 to 0.3. A hyperintense region was present on T1-weighted images in the center of the pituitary gland in 64% of the dogs. At necropsy the pituitary glands were grossly and histologically normal. No pituitary gland measurements were performed at necropsy.  相似文献   

羊生长激素的提取及生物化学和生物活性的测定     

郭亚平  夏国良  杨传任 《中国农业大学学报》1990,(4):442-446

600 g 冰冻羊垂体经过酸性溶液提取、硫酸铵的分级分离和 DEAE-纤维素柱层析得纯品(1),其得率为0.08g/kg,最后将部分纯品(1)过 Sephadex G-100分子筛,得到高纯的羊生长激素[纯品(2)]。提取的羊生长激素具有相当高的理化均一性,纯品(2):聚丙烯酰胺凝胶电泳呈现一条主带和二条酸性小带;聚丙烯酰胺等电聚焦电泳呈现二条带,其等电点分别为 pH7.35和 pH7.40,SDS—电泳呈现二条很难分开的带,其平均分子量为20 100道尔顿;用DNS-CI 法测得的 N-末端氨基酸是2个,丙氨酸和苯氨酸。纯品(1)理化均一性稍差:SDS—电泳较纯品(2)多出两条分子量低的带;等电聚焦电泳多出六条酸性小带。除此之外,其他理化性质同纯品(2)。用大白鼠胫骨实验测定生物活性,测得纯品(1)可使垂体大白鼠胫骨软骨盘的宽度相对增加79%。未对纯品(2)进行生物活性测定。用羊催乳素放射免疫药盒测定,纯品(1)和纯品(2)与羊催乳素均无交叉反应。  相似文献   

LRH─A3、hCG和PMSG对体外培养条件下牦牛垂体组织LH和FSH分泌的调节     

刘宗平  余四九  陈北亨 《中国兽医学报》1997,(1)

促卵泡素３号（ＬＲＨ－Ａ３）、人绒毛膜促性腺激素（ｈＣＧ）和孕马血清促性腺激素（ＰＭＳＧ）等３种外源性激素均可增加体外培养条件下牦牛垂体组织分泌ＬＨ和ＦＳＨ的能力。培养液中ＬＨ和ＦＳＨ含量与加入的ＬＲＨ－Ａ３量呈正相关，与加入的ＰＭＳＧ和ｈＣＧ的量无显著关系  相似文献   

奶牛难产激发应激性急性肾上腺皮质功能不全——心衰、水电解质严重失调辩析     

邱立和  陈贵喜  李宏全 《山西农业大学学报(自然科学版)》1992,(2)

应激性急性肾上腺皮质功能不全症的病理机制十分复杂,目前人医的各类文献中大都以“垂体—肾上腺轴”功能不全、功能衰竭、或发生广泛性出血坏死性病演作解释。本病在奶牛分娩难产过程中并不少见,病牛的症状表现以心衰和失钠性低血症为主征。但在兽医临床上由于认识不足,曾有不少中外学者将奶牛产后卧地不起的各类疾病,含糊地统称为“母牛睡倒爬不起来综合征”;更由于救治不当,病牛常以淘汰或死亡告终。本文通过对一具体典型病例辨析,着重讨论了本病的基本病理反应和确立诊断依据,强调对本病救护施治时应遵循的基本原则,供同道们在分析和解决这一实际问题时参考。  相似文献   

Evaluation of individual low‐dose dexamethasone suppression test patterns in naturally occurring hyperadrenocorticism in dogs          下载免费PDF全文

Michael Bennaim  Robert E. Shiel  Christopher Forde  Carmel T. Mooney 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2018,32(3):967-977

  相似文献   

Equine pituitary pars intermedia dysfunction: current understanding and recommendations from the Australian and New Zealand Equine Endocrine Group          下载免费PDF全文

CJ Secombe  SR Bailey  MA de Laat  KJ Hughes  AJ Stewart  JM Sonis  RHH Tan 《Australian veterinary journal》2018,96(7):233-242

The purpose of this article is to provide a review of the current knowledge and opinions about the epidemiology, clinical findings (including sequelae), diagnosis, treatment and monitoring of equine pituitary pars intermedia dysfunction, particularly in the Australian context. This information and the recommendations provided will assist practitioners in making informed decisions regarding the diagnosis and management of this disorder.  相似文献   

Initial analytic quality assessment and method comparison of an immunoassay for adrenocorticotropic hormone measurement in equine samples          下载免费PDF全文

Katherine L. Irvine  Kay Burt  Andrew J. Hill  Stephanie Shaw  Kostas Papasouliotis 《Veterinary clinical pathology / American Society for Veterinary Clinical Pathology》2016,45(1):154-163

  相似文献   

Effect of sirolimus on insulin dynamics in horses     

Demia J. de Tonnerre  Carlos E. Medina Torres  Darko Stefanovski  Mary A. Robinson  Kate L. Kemp  François-René Bertin  Andrew W. van Eps 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2023,37(2):703-712

  相似文献   

Luteinizing hormone (LH) response to different doses of synthetic gonadotropin releasing hormone (GnRH) in prepubertal gilts     

S Rojanasthien  A Kunavongkrit  S Einarsson 《Acta veterinaria Scandinavica》1986,27(2):257-266

The object of this investigation was to study luteinizing hormone (LH) response to different doses of synthetic gonadotropin-releasing hormone (GnRH) in prepubertal gilts. Four crossbred prepubertal gilts, 128–134 days old and body weight 57–63 kg, were used in this study. Four doses, 0. 5, 25 and 125 μg, of GnRH were administered via a jugular vein catheter in a latin square design. Each treatment consisted of 3 injections at 90 min intervals. Frequent blood samples were taken during a period of 90 min before up to 90 min after treatment. Total LH responses were measured from post-treatment samples as the area under the curve above base level obtained from pre-treatment samples. A positive relationship between GnRH dose and LH release was obtained in all gilts, except for 1 treatment given to a gilt with high plasma level of oestradiol-17β on the day of treatment. This study has demonstrated the responsiveness of the pituitary gland by LH release to different doses of GnRH in 4.5-month-old prepubertal gilts.  相似文献   

Single nucleotide polymorphism identification, linkage and radiation hybrid mapping of the porcine pituitary adenylate cyclase-activating polypeptide type I receptor gene to chromosome 18     

S. Kollers  B. Mote  M.F. Rothschild  G. Plastow  & D. Rocha 《Zeitschrift für Tierzüchtung und Züchtungsbiologie》2006,123(6):414-418

Pituitary adenylate cyclase‐activating polypeptide (PACAP) is a neuropeptide with diverse biological actions. Type I PACAP receptors (PACAPR) are specific for PACAP, whereas type II and III PACAPRs are less restricted. To localize and analyse the variation of this gene, a 559‐bp long intronic fragment of the porcine PACAPR gene was amplified by polymerase chain reaction and sequenced in samples from five different pig breeds. One single nucleotide polymorphism was identified and its allele frequency was determined in all five breeds. Linkage analysis in a Berkshire × Yorkshire reference family placed the PACAPR gene on chromosome 18, between SW787 and S0062 (SW787– 8.1 cM –PACAPR– 3.0 cM –S0062). Radiation hybrid mapping confirmed that the PACAPR gene was linked to SW1682 on chromosome 18 (28.8 cR₃₀₀₀; LOD = 10.4).  相似文献