Colostral Trypsin-Inhibitor Capacity in Different Animal Species |
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| Authors: | M Sandholm T Honkanen-Buzalski |
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| Institution: | Department of Pharmacology and Toxicology, College of Veterinary Medicine, Hämeentie 57, 00550 Helsinki 55, Finland |
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| Abstract: | Colostral trypsin-inhibitor capacity was monitored during the first two weeks from parturition. The colostrum of the mare, sow, cow and ewe showed high antitrypsin activity at parturition, decreasing to about one hundredth during the first week. Canine milk remained on a relatively high antitrypsin level, and human milk was poor in antitrypsin from childbirth. The antitrypsin content seems to parallel the known changes in the colostral immunoglobulin levels of different species. The role of antitrypsin in protection of immunoglobulins from proteolytic damage during passive transfer of immunity to the newborn is obvious. |
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| Keywords: | colostrum trypsin inhibitor protease inhibitors colostral albumin |
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