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Genetic characterization of a betanodavirus isolated from a clinical disease outbreak in farm‐raised tilapia Oreochromis niloticus (L.) in Thailand |
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| Authors: | J Keawcharoen S Techangamsuwan A Ponpornpisit E D Lombardini T Patchimasiri N Pirarat |
| Institution: | 1. Department of Veterinary Microbiology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand;2. Department of Pathology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand;3. Department of Veterinary Medicine, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand;4. Divisions of Comparative Pathology and Research Veterinary Medicine, Department, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand;5. Pathology Section, National Institute of Animal Health, Kasetsart Klang, Chatuchak, Bangkok, Thailand |
| Abstract: | Betanodavirus infection was diagnosed in larvae of farm‐raised tilapia Oreochromis niloticus (L.), in central Thailand. Extensive vacuolar degeneration and neuronal necrosis were observed in histological sections with positive immunohistochemical staining for betanodavirus. Molecular phylogenetic analysis was performed based on the nucleotide sequences (1333 bases) of the capsid protein gene. The virus strain was highly homologous (93.07–93.88%) and closely related to red‐spotted grouper nervous necrosis virus (RGNNV). |
| Keywords: | betanodavirus farm‐raised tilapia Genetic characteristic Thailand |