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从虚瘀痰毒探讨口腔黏膜下纤维化的发病机制
作者姓名:谭劲  吴丹  刘寻  周小青
作者单位:湖南中医药大学第一附属医院, 湖南 长沙 410007;湖南中医药大学中医诊断研究所, 湖南 长沙 410007,湖南中医药大学研究生院, 湖南 长沙 410007,湖南中医药大学研究生院, 湖南 长沙 410007,湖南中医药大学中医诊断研究所, 湖南 长沙 410007
基金项目:国家自然科学基金资助项目(81373701)。
摘    要:口腔黏膜下纤维化(oral submucous fibrosis ,OSF)是一种慢性进行性具有癌变倾向的口腔黏膜疾病。本文结合该病临床疗效及致病特点,从毒瘀痰虚等方面探讨了OSF的中医病因病机,提示OSF致病与邪毒外侵、痰瘀互结、正气虚弱密切相关,临床采取扶正祛邪,祛瘀化痰法相结合,可改善患者临床症状,阻止疾病进一步发展。

关 键 词:口腔黏膜下纤维化        
收稿时间:2015/12/3 0:00:00

Discussion on the Pathogenesis of Oral Submucous Fibrosis from Deficiency, Blood Stasis, Phlegm and Toxin
Authors:TAN Jin  WU Dan  LIU Xun and ZHOU Xiaoqing
Institution:The First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, Hunan 410007, China;Institution of Diagnosis of Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan 410007, China,Graduate School, Hunan Unversity of Chinese Medicine, Changsha, Hunan 410007, China,Graduate School, Hunan Unversity of Chinese Medicine, Changsha, Hunan 410007, China and Institution of Diagnosis of Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan 410007, China
Abstract:Oral submucous fibrosis (OSF) is a chronic and progressive oral mucosal disease with cancerous tendency. This paper discusses TCM pathogenic mechanism of OSF based on the therapeutic effect and pathogenic characteristics of the disease. The etiology of OSF is closely related with totoxic invasion, integration of phlegm and blood stasis, and Qi deficiency. The "strengthen body resistance and eliminating evil" combined with "remove blood stasis and reducing phlegm" methods are taken in clinic, which can improve the clinical symptoms of patients and prevent the further development of diseases.
Keywords:oral submucous fibrosis  deficiency  blood stasis  phlegm  toxin
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