| I型鸭疫里默氏杆菌荚膜免疫的研究 |
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| 引用本文： | 齐冬梅.I型鸭疫里默氏杆菌荚膜免疫的研究[J].中国兽药杂志,2009,43(4):17-19. |
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| 作者姓名： | 齐冬梅 |
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| 作者单位： | 广东永顺生物制药有限公司 |
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| 基金项目： | 广东省中小企业专项资金技术改造项目基金 |
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| 摘 要： | 用盐浸法提取了I型鸭疫里默氏杆菌（RA）的荚膜，并制成油佐剂疫苗。其免疫原性测定结果表明：用荚膜粗提物免疫雏鸭可得到很好的免疫保护效果（9／10）。同时进行了RA荚膜油佐剂疫苗与各常规佐剂疫苗的免疫效力比较，免疫保护效果依次为：英膜油乳剂苗、油乳剂灭活苗、蜂胶灭活苗、铝胶RA灭活苗、无佐剂RA灭活苗。结果显示，鸭疫里默氏杆菌英膜免疫的研究为进一步研制亚单位疫苗打下基础。
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| 关 键 词： | I型鸭疫里默氏杆菌 英膜 免疫 |
| 收稿时间： | 2008/12/23 0:00:00 |
| 修稿时间： | 2009/1/16 0:00:00 |
Study on Riemerella anatipestifer (I) Capsular Polysaccharide Vaccine |
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| qidongmei.Study on Riemerella anatipestifer (I) Capsular Polysaccharide Vaccine[J].Chinese Journal of Veterinary Drug,2009,43(4):17-19. |
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| Authors: | qidongmei |
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| Institution: | QI Dong - mei, LAI Yue - hui, WU Yue - sheng, CAI zhi - song, WANG Zhuo - ming ( Guangdong Winsun Bio - Pharmaceutical Co. ,Ltd. , Guangzhou 511356;China) |
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| Abstract: | In this study, Capsular Polysaccharide were extracted by high-concentraction NaCl, and developed the oil-adjuvant vaccine to vaccinate the 4-day-ducklings. The result of potency test for this vaccine showed that Capsular Polysaccharide vaccine had good protective efficiency (9/10). The potency comparative test of this vaccine with other adjuvant Riemerella anatipestifer (RAI) inactivated vaccines were done in the same time. The best one was Capsular Polysaccharide oil-adjuvant vaccine and the other successively were oil-adjuvant inactivated vaccine, propolis-adjuvant inactivated vaccine, aluminium hydroxide -adjuvant inactivated vaccine and no-adjuvant inactivated vaccine. |
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| Keywords: | Riemerella anatipestifer (I) Capsular Polysaccharide vaccination |
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