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Pelger–Huët Anomaly in a cat
Authors:Pierre Deshuillers  Rose Raskin  Joanne Messick
Institution:Department of Comparative Pathobiology, Purdue University College of Veterinary Medicine, , West Lafayette, IN, USA
Abstract:A 14‐year‐old, spayed female Domestic Shorthair cat was referred to the Purdue University Veterinary Teaching Hospital (PUVTH) for iodine 131 treatment of hyperthyroidism. Upon arrival, a biochemistry profile and a CBC were performed. Approximately 50% of the neutrophils and all the eosinophils observed were hyposegmented with a mature, condensed chromatin pattern. Nuclei had a band to “dumbbell” shape, and rarely a round shape, suggesting a Pelger–Huët anomaly or a pseudo Pelger–Huët. Based on both a negative FeLV and FIV tests, the absence of any clinical signs to support an inflammatory process, and the persistence of this granulocytic morphology 6 months after its previous admission to the PUVTH, a diagnosis of Pelger–Huët anomaly was established in this cat.
Keywords:Blood smear  Cell‐Dyn 3500  granulocytes  lamin B receptor  Procyte Dx  pseudo Pelger–  Huë  t  scattergram
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