| 日粮添加精氨酸对肥育猪免疫功能的调节作用 |
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| 引用本文： | 柏美娟,孔祥峰,印遇龙,谭碧娥,黄瑞林,李铁军,宋小燕,耿梅梅.日粮添加精氨酸对肥育猪免疫功能的调节作用[J].扬州大学学报(农业与生命科学版),2009,30(3). |
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| 作者姓名： | 柏美娟 孔祥峰 印遇龙 谭碧娥 黄瑞林 李铁军 宋小燕 耿梅梅 |
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| 作者单位： | 1. 中国科学院,亚热带农业生态研究所,湖南,长沙,410125;中国科学院,研究生院,北京,100039
2. 中国科学院,亚热带农业生态研究所,湖南,长沙,410125 |
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| 基金项目： | 国家重点基础研究发展计划项目，国家自然科学基金资助项目，国家"十一五"科技支撑计划项目 |
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| 摘 要： | 以杜×(大×长)三元杂种猪为研究对象,将其分为2组,分别饲喂基础日粮和添加1%精氨酸日粮.测定试验猪血液白细胞分类计数,血清免疫球蛋白和细胞因子水平、淋巴细胞增殖活性以及脾脏IL-2、TNF-α和IFN-γ的mRNA表达水平,探讨日粮添加精氨酸对肥育猪免疫功能的调节作用.结果表明:日粮中添加1%精氨酸可显著增加单核细胞数和百分比、淋巴细胞百分比和增殖活性及血清IgG和IL-2水平,显著降低中性粒细胞数和百分比及血清TNF-α水平;明显增加脾脏IL-2和IFN-γ表达水平,降低TNF-α表达水平.结果提示,精氨酸可通过调节肥育猪的细胞和体液免疫水平,从而增强机体免疫功能.
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| 关 键 词： | 肥育猪 精氨酸 免疫功能 |
Regulation of dietary supplemental arginine on immune response in fattening pigs |
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| BAI Mei-juan,KONG Xiang-feng,YIN Yu-long,TAN Bie,HUANG Rui-lin,LI Tie-jun,SONG Xiao-yan,GENG Mei-mei.Regulation of dietary supplemental arginine on immune response in fattening pigs[J].Journal of Yangzhou University:Agricultural and Life Science Edition,2009,30(3). |
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| Authors: | BAI Mei-juan KONG Xiang-feng YIN Yu-long TAN Bie HUANG Rui-lin LI Tie-jun SONG Xiao-yan GENG Mei-mei |
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| Institution: | BAI Mei-juan1,2,KONG Xiang-feng1,YIN Yu-long1,TAN Bi-e1,HUANG Rui-lin1,LI Tie-jun1,SONG Xiao-yan1,GENG Mei-mei1 (1.Inst of Subtrop Agric,the Chinese Acad of Sci,Changsha 410125,China,2.Sch of Grad,Beijing 100039,China) |
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| Abstract: | This study was conducted to evaluate the effects of arginine on immune response in fattening pigs.Twenty Duroc×Landrace× Yorkshire pigs with about 50 kg of body weight were randomly assigned to 2 treatment groups(10pigs per group)representing the addition of 0 or 1% arginine to basal diets.On 60 days after initiation of the addition,total and differential counts of leucocytes,serum levels of immunoglobulins(Ig)and cytokines,and proliferation activity of peripheral lymphocytes were determined,as well as mRNA expression levels of IL-2,TNF-α and IFN-γ in spleen.The results showed that dietary supplementation with 1% arginine increased the monocyte number,percentages of monoeyte and lymphocyte,proliferation activity of lymphocyte,and serum contents of IgG and IL-2(P<0.05),as well as gene expression of IL-2 and IFN-γ(P>0.05),and decreased the number and percentage of neutrophils,and serum content of TNF-α(P<0.05),as well as expression level of TNF-α(P>0.05)in comparison with the control group.In conclusion,these findings suggest that the 1% arginine as a dietary additive enhances the immune function of fattening pigs by modulating the cellular and humoral immune responses. |
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| Keywords: | fattening pigs arginine immune function |
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