| 蜂胶的免疫增强作用及其在疫苗中的应用 |
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| 引用本文： | 王茹,谢印乾,沈志强,缪晓青.蜂胶的免疫增强作用及其在疫苗中的应用[J].中国畜牧兽医,2007,34(2):93-95. |
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| 作者姓名： | 王茹 谢印乾 沈志强 缪晓青 |
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| 作者单位： | 1.福建农林大学蜂学院,福州 350002；2.山东省滨州畜牧兽医研究院,滨州 256618 |
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| 摘 要： | 蜂胶极其复杂的化学成分，决定了它具有广泛的生物学作用。其中，蜂胶具有抗菌、抗病毒及增强机体免疫功能等作用；蜂胶颗粒能与抗原相互交联成类免疫刺激复合物（ISCOM）结构，具有抗原“仓库”和免疫刺激复合物作用；蜂胶本身没有抗原性，但可起到免疫佐剂的作用，促进抗体的生成；这些作用及其间的协同作用决定了蜂胶是一种天然的免疫增强剂。自20世纪60年代以来，蜂胶的免疫增强作用及其在疫苗佐剂中的研究不断深入，并取得了满意效果,这为新型而有效疫苗的研制和开发提供一些理论指导。
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| 关 键 词： | 蜂胶 免疫增强 疫苗佐剂 |
| 文章编号： | 1671-7236（2007）02-0093-03 |
| 修稿时间： | 2006-08-04 |
The Immunological Enhancement and Application of Propolis |
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| WANG Ru,XIE Yin-qian,SHEN Zhi-qiang,MIAO Xiao-qing.The Immunological Enhancement and Application of Propolis[J].China Animal Husbandry & Veterinary Medicine,2007,34(2):93-95. |
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| Authors: | WANG Ru XIE Yin-qian SHEN Zhi-qiang MIAO Xiao-qing |
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| Institution: | 1.Fujian Bees Institute, Fujian Agriculture and Forestry University, Fuzhou 350002,China; 2.Institute of Animal Husbandry and Veterinary Medicine, Binzhou Academy of Shandong, Binzhou 256618,China |
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| Abstract: | Propolis extremely complex chemical composition determines its broad biological actions.Propolis have anti-bacterial,anti-virus and immunological enhancement etal: particles and antigens link with each other into composites(ISCOM) structure with antigen "warehouse" and the role of immune stimulating compounds: although propolis itself has no antigen property,it plays a part as an immune adjuvant in the promotion of antibody generation.the role and synergies between themselves decide propolis is a immunopotentiator.Since the 1960s,its immunological enhancement and its application in vaccine adjuvant are futher researched,and have achieved satisfactory results,which provide some theoretical guidance to the research and development of new vaccines. |
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| Keywords: | propolis immunological enhancement vaccine adjuvant |
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