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猪肠道微生物及其代谢产物与肠道屏障研究进展
引用本文:张德明,黄嘉訸,李劲树,郑红梅,王少英,杨公社,史新娥.猪肠道微生物及其代谢产物与肠道屏障研究进展[J].畜牧兽医学报,2022,53(5):1334-1344.
作者姓名:张德明  黄嘉訸  李劲树  郑红梅  王少英  杨公社  史新娥
作者单位:陕西省动物遗传育种与繁殖重点实验室 西北农林科技大学动物科技学院动物 脂肪沉积与肌肉发育实验室, 杨凌 712100
基金项目:陕西省重点研发计划(2020NY-004);
摘    要:肠道微生物参与营养物质代谢,影响猪的健康和发育,当肠道微生物发生紊乱,会造成猪腹泻并引起炎症反应,因此肠道微生物对猪的健康起着至关重要的作用。本文从肠道微生物在仔猪不同发育阶段的分布、肠道微生物的代谢产物对肠道健康的影响机制和肠道微生物与肠道屏障之间的关系进行阐述,并探讨了目前肠道健康研究的进展以及今后的研究方向,旨在为猪肠道健康调控提供理论参考。

关 键 词:肠道微生物  代谢产物  肠道健康    
收稿时间:2021-08-09

Research Progress of Gut Microbiota,Metabolites and Gut Barrier in Pigs
ZHANG Deming,HUANG Jiahe,LI Jinshu,ZHENG Hongmei,WANG Shaoying,YANG Gongshe,SHI Xin’e.Research Progress of Gut Microbiota,Metabolites and Gut Barrier in Pigs[J].Acta Veterinaria et Zootechnica Sinica,2022,53(5):1334-1344.
Authors:ZHANG Deming  HUANG Jiahe  LI Jinshu  ZHENG Hongmei  WANG Shaoying  YANG Gongshe  SHI Xin’e
Institution:Laboratory of Animal Fat Deposition & Muscle Development, College of Animal Science and Technology, Northwest A&F University, Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, Yangling 712100, China
Abstract:Gut microbiota are involved in nutrient metabolism and affect the health and development of pigs. Disturbed gut microbiota can cause diarrhea and immune response in pigs. Therefore, gut microbiota play a vital role in pig health. This article reviwed the distribution of gut microbiota in different development stages of piglets, the influence mechanism of gut microbiota metabolites on gut health, and the relationship between gut microbiota and gut barrier. As well discussed the current research progress of gut health and future research direction, aiming to provide theoretical reference to modulate intestinal networks to maintain swine health.
Keywords:gut microbiota  metabolites  gut health  pigs  
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