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Impact of oral melatonin on the electroretinogram cone response |
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| Authors: | Anne-Marie Gagné Konstantin V Danilenko Serge G Rosolen Marc Hébert |
| Institution: | 1. Centre de Recherche Université Laval Robert-Giffard, Faculty of Medicine, Université Laval, Québec, Canada 2. Institute of Internal Medicine, Siberian Branch of the Russian Academy of Medical Sciences, Novosibirsk, Russia 3. Centre de Recherche - Institut de la Vision UMR S968, INSERM-UPMC Paris 6, Paris, France 4. Clinique Vétérinaire Voltaire, Asnières, France |
| Abstract: | BackgroundIn the eye, melatonin plays a role in promoting light sensitivity at night and modulating many aspects of circadian retinal physiology. It is also an inhibitor of retinal dopamine, which is a promoter of day vision through the cone system. Consequently, it is possible that oral melatonin (an inhibitor of retinal dopamine) taken to alleviate circadian disorders may affect cone functioning. Our aim was to assess the impact of melatonin on the cone response of the human retina using electroretinography (ERG). |
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