| 114例HBsAg阳性孕妇及其新生儿PBMC 感染HBV的状况 |
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| 引用本文： | 王效军,王素萍,李铁钢,冯永亮.114例HBsAg阳性孕妇及其新生儿PBMC 感染HBV的状况[J].湛江医学院学报,2006,24(2):131-133. |
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| 作者姓名： | 王效军 王素萍 李铁钢 冯永亮 |
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| 作者单位： | 广东医学院预防医学教研室 广东湛江524023(王效军)，山西医科大学流行病学教研室 山西太原030001(王素萍，冯永亮)，广州市疾病预防控制中心 广东广州510080(李铁钢) |
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| 摘 要： | 目的:了解HB sA g阳性孕妇及其新生儿PBM C HBV感染状况。方法:采用原位杂交(ISH)技术检测114例孕妇和新生儿PBM C涂片中HBV DNA。结果:114例HB sA g阳性孕妇及其新生儿PBM C HBV DNA的检出率分别为28.07%(32/114)和32.46%(37/114);HB sA g阳性孕妇与其新生儿之间的PBM C HBV感染存在一致性(K app a=0.52,P<0.01)。结论:证实HB sA g阳性孕妇与其新生儿之间的PBM C HBV感染存在一致性。
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| 关 键 词： | 外周血单个核细胞 乙型肝炎病毒 原位杂交 |
| 文章编号： | 1005-4057(2006)02-0131-03 |
| 收稿时间： | 12 26 2005 12:00AM |
| 修稿时间： | 02 20 2006 12:00AM |
The status of HBV infection in peripheral blood mononuclear cells from 114 HBsAg-positive mothers and their newborns |
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| WANG Xiao-jun,WANG Su-ping,LI Tie-gang,FENG Yong-Liang.The status of HBV infection in peripheral blood mononuclear cells from 114 HBsAg-positive mothers and their newborns[J].Journal of Guangdong Medical College,2006,24(2):131-133. |
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| Authors: | WANG Xiao-jun WANG Su-ping LI Tie-gang FENG Yong-Liang |
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| Institution: | Department of Preventive Medicine, Guangdong Medical College, Zhanjiang 524023, China |
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| Abstract: | Objective:To observe the status of HBV infection in peripheral blood mononuclear cells(PBMC) from the HBsAg-positive mothers and their neonates.Methods:In situ hybridization(ISH) was used to detect HBV DNA in PBMC smear from 114 HBsAg-positive mothers and theirs newborns.Results:The positive rates of the PBMC HBV infection of the mothers and their neonates were 28.07% and 32.46%,respectively.There was an agreement of the HBV infection status between the mothers and their newborns(Kappa=0.52,P<0.01).Conclusion:The result suggests that the HBV infection status from the mothers agrees with that from their newborns. |
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| Keywords: | peripheral blood mononuclear cells hepatitis B virus in situ hybridization |
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