| 醋酸甲羟孕酮(MPA)原位凝胶植入剂对鼠抗生育作用的研究 |
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| 引用本文： | 李婷婷.醋酸甲羟孕酮(MPA)原位凝胶植入剂对鼠抗生育作用的研究[J].中国兽药杂志,2010,44(1):38-40. |
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| 作者姓名： | 李婷婷 |
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| 作者单位： | 西南大学药学院,重庆北碚400716 |
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| 摘 要： | 为达到城市宠物药物避孕的效果，开发醋酸甲羟孕酮原位凝胶植入剂（MPA—PLA）。采用MPA—PLA进行动物体内实验，考察MPA—PLA对小鼠避孕时间和繁殖率的影响及其对大鼠血清中雌二醇（E2）和促黄体生成激素（LH）激素浓度水平的影响。结果表明MPA—PLA对大、小鼠具有长效抗生育作用。
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| 关 键 词： | 醋酸甲羟孕酮原位凝胶植入剂 长效缓释 抗生育作用 |
| 收稿时间： | 2009/2/25 0:00:00 |
| 修稿时间： | 2009/4/10 0:00:00 |
Studies on The Anti-fertility Effeet of In Situ Gel Implants Containing Medroxy progesterone acetate (MPA-PLA) in mice |
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| LITINGTING.Studies on The Anti-fertility Effeet of In Situ Gel Implants Containing Medroxy progesterone acetate (MPA-PLA) in mice[J].Chinese Journal of Veterinary Drug,2010,44(1):38-40. |
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| Authors: | LITINGTING |
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| Institution: | Southwest University |
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| Abstract: | To estimating the Sustained Release efficiency of in situ gel implants containing Medroxy progesterone acetate and investigate effection of reproduction rate in mice and detect the level of E2 and LH in serum of rats .The results show that MPA-PLA could significantly prolong the anti-birth duration ,suggest that MPA-PLA has long-term anti-fertility effeet. |
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| Keywords: | Implants Sustained release Anti-fertility effete |
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