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噬菌体制剂对母猪生产性能、免疫指标及粪便微生物的影响
引用本文:葛龙,贺永超,石永顺,李鑫,汤莉,单子琦,于凌云,潘强.噬菌体制剂对母猪生产性能、免疫指标及粪便微生物的影响[J].饲料研究,2021(3):106-109.
作者姓名:葛龙  贺永超  石永顺  李鑫  汤莉  单子琦  于凌云  潘强
作者单位:北京诺安百特生物技术有限责任公司;青岛诺安百特生物技术有限公司
摘    要:试验旨在研究噬菌体对母猪生产性能、免疫指标和粪便微生物数量的影响。试验选取96头健康长大二元母猪,随机分为4组,每组24头猪。空白对照组母猪饲喂基础日粮,试验组1、试验组2和试验组3分别在基础日粮中加入100、300、500 g/t的沙门氏菌噬菌体、大肠杆菌噬菌体和产气荚膜梭菌噬菌体组成的复合制剂,试验周期为35 d。结果显示:试验组2和试验组3相比空白对照组的窝产活仔数、断奶活仔数、平均奶均重和平均日增重均显著提高(P<0.05)。试验组1相比空白对照组的断奶活仔数、平均奶均重和平均日增重均显著提高(P<0.05)。在分娩当日,相比空白对照组,试验组3的免疫球蛋白A (IgA)含量显著提高(P<0.05)。试验组2和试验组3的免疫球蛋白M (IgM)和免疫球蛋白G (IgG)含量显著提高(P<0.05)。在断奶当日,相比空白对照组,3种剂量组的IgA、IgM和IgG含量均显著提高(P<0.05)。试验组2和试验组3的乳酸菌含量显著增加(P<0.05)。3种剂量组的大肠杆菌和沙门氏菌数量均显著降低(P<0.05)。试验表明,添加复合噬菌体制剂能提高母猪生产性能,提高机体免疫力,改善肠道微生态环境,日粮中添加300 g/t复合噬菌体制剂比较合适。

关 键 词:噬菌体  母猪  生产性能  免疫指标  粪便微生物

Effect of bacteriophage preparation on production performance,immune indexes and fecal microorganism of sows
GE Long,HE Yong-chao,SHI Yong-shun,LI Xin,TANG Li,SHAN Zi-qi,YU Ling-yun,PAN Qiang.Effect of bacteriophage preparation on production performance,immune indexes and fecal microorganism of sows[J].Feed Research,2021(3):106-109.
Authors:GE Long  HE Yong-chao  SHI Yong-shun  LI Xin  TANG Li  SHAN Zi-qi  YU Ling-yun  PAN Qiang
Abstract:The objective of the study was to evaluate the effects of bacteriophage preparation on production performance,immune index and fecal microorganism of sows. 96 healthy Landrace×Yorkshire sows were randomly divided into four groups with 24 sows in each group. The experimental period was 35 d. The sows in control group were fed the basal diet,and the test group 1, 2 and 3 were fed the basal diet supplemented with 100, 300, 500 g/t of coliphage, Salmonella phage,Escherichia coli phage and Clostridium percapsulens phage, respectively. The results showed that compared with the control group, litter born alive, weaned alive, average milk weight and average daily gain in test group 2 and group 3 were significantly increased(P<0.05). Compared with the control group, the live litter number, average milk weight and average daily gain in test group 1 were significantly increased(P<0.05). On the day of delivery, compared with the control group,the IgA content in test group 3 was significantly increased(P<0.05). The IgM content and IgG in test group 2 and group 3 were significantly increased(P<0.05). On the weaning day, compared with the control group, IgA, IgM and IgG of the three dose groups were significantly increased(P<0.05). Compared with the blank control group, the number of lactic acid bacteria in test groups two and three was significantly increased(P<0.05). The numbers of Escherichia coli and Salmonella in three test groups were significantly decreased(P<0.05). In conclusion, adding complex bacteriophage preparation can improve the performance of sows, improve the body immunity, and improve the intestinal microecological environment. 300 g of complex bacteriophage preparation per ton of sows basal diet is a more appropriate dose.
Keywords:phage  sows  production performance  immune indexes  fecal microorganism
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