Gastrointestinal Hemodynamics in Dogs with Nonfood Induced Atopic Dermatitis |
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| Authors: | V Bruet J Brune A Pastor L Imparato A Roussel P Bourdeau JC Desfontis |
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| Institution: | 1. Dermatology, parasitology, mycology unit, LUNAM, Oniris, , Nantes, France;2. Animal pathophysiology and functional pharmacology , LUNAM, Oniris, , Nantes, France;3. Diagnostic imaging unit, LUNAM, Oniris, , Nantes, France |
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| Abstract: | Background Canine atopic dermatitis can be a result of exposure to aeroallergens or trophallergens. Hemodynamic alterations occur in dogs with food hypersensitivity. Hypothesis/Objectives To evaluate if hemodynamic alterations occur in dogs with NFICAD with lowered resistance to diastolic flow at fasting, after feeding, or both. Animals Ten healthy dogs and 22 dogs with NFICAD were included from the hospital population. Methods Blinded prospective study. Peak systolic velocity (PSV), end diastolic velocity (EDV), mean velocity (MV), pulsatility index (PI), resistive index (RI) and PSV/EDV ratio were measured at fasting for both arteries (cranial mesenteric artery CMA], celiac artery CA]) and at 40 minutes after feeding in CMA and at 60 minutes in CA. The results were analyzed statistically with a mixed model. Results There was no difference detected between groups of dogs for any variable except EDV during fasting (P = .01). Conclusions and Clinical Importance There is no decrease in resistance in NFICAD to diastolic flow. This observation could be explained by the absence intestinal inflammation in NFICAD. |
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| Keywords: | Atopy Intestinal permeability Skin Vascular flow |
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