| 霉菌毒素对动物肠道功能的影响及其作用机制研究进展 |
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| 引用本文： | 陈豪,何流琴,刘娣,杨玲媛.霉菌毒素对动物肠道功能的影响及其作用机制研究进展[J].动物营养学报,2022,34(2):772-782. |
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| 作者姓名： | 陈豪 何流琴 刘娣 杨玲媛 |
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| 作者单位： | 湖南农业大学动物科学与技术学院,长沙 410128;湖南师范大学生命科学学院,动物肠道功能湖南省重点实验室,长沙 410081;黑龙江省农业科学院畜牧研究所,哈尔滨 150086 |
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| 基金项目： | 中国科协青年托举人才项目(2019QNRC001);广西桂林市科技计划项目(2020010901);广西重点研发计划(桂科AB19259012);国家自然科学基金面上项目(31872370);湖湘高层次人才聚集工程项目(2018RS3111);湖南省动物肠道生态与健康国际科技创新合作基地开放基金项目。 |
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| 摘 要： | 霉菌毒素属于霉菌次级代谢产物,具有种类多、分布广、毒性大的特点.霉菌毒素作为畜牧业中的"隐形杀手",不仅严重降低了饲料品质,而且常存在于饲料原料中,影响动物机体健康,直接或间接造成食品安全问题.肠道作为消化吸收的主要场所,对霉菌毒素的刺激具有强烈的抵御和免疫作用,同时也深受霉菌毒素的损伤.玉米是主要的饲料原料之一,而黄...
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| 关 键 词： | 霉菌毒素 肠道菌群 免疫功能 氧化应激 营养代谢 |
Research Progress of Effects of Mycotoxin on Intestinal Function and Its Mechanism |
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| CHEN Hao,HE Liuqin,LIU Ti,YANG Linyuan.Research Progress of Effects of Mycotoxin on Intestinal Function and Its Mechanism[J].Acta Zoonutrimenta Sinica,2022,34(2):772-782. |
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| Authors: | CHEN Hao HE Liuqin LIU Ti YANG Linyuan |
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| Institution: | (College of Animal Science and Technology,Hunan Agricultural University,Changsha 410128,China;Hunan Provincial Key Laboratory of Animal Nutritional Physiology and Metabolic Process,College of Life Science,Hunan Normal University,Changsha 410081,China;Institute of Animal Husbandry,Heilongjiang Academy of Agricultural Sciences,Harbin 150086,China) |
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| Abstract: | Mycotoxins are secondary metabolites of fungi,which are characterized by many kinds,wide distribution and high toxicity. Mycotoxins,as the“invisible killer”in animal husbandry,not only seriously reduce the quality of feed,but also often exist in feed materials,affecting animal health and directly or indirectly causing food safety problems. As the main place of digestion and absorption,intestinal tract has strong resistance and immunity to the stimulation of mycotoxins,and it is also deeply affected by mycotoxins. Maize is one of the main feed materials,and aflatoxin,deoxynivalenol and zearalenone are the main mycotoxins in maize,therefore,it is particularly important to understand the toxic mechanism of these three mycotoxins. In this paper,based on the research status at home and abroad,take these three mycotoxins as examples,the effects of mycotoxins on Intestinal barrier,immune function,antioxidant function,microecological balance and nutrient metabolism were reviewed,which provided new ideas and theoretical basis for reducing the harm of mycotoxins in feed and developing products for degrading mycotoxins. At the same time,it also has great significance to improve the quality of livestock and poultry meat and food strategic security in China.Chinese Journal of Animal Nutrition,2022,34(2):772-782] |
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| Keywords: | mycotoxins intestinal flora immune function oxidative stress nutrient metabolism |
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