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A Case of Feline Gastrointestinal Eosinophilic Sclerosing Fibroplasia
Authors:Manabu Suzuki  Miyako Onchi  Masakazu Ozaki
Institution:1. Small Animal Pathology Service Inc., 86-1 Hanare, Tsukuba, Ibaraki 305-0857, Japan;2. Sumika Technoservice Corporation, 1-98 Kasugade-naka 3-chome, Konohanaku, Osaka 554-8558, Japan
Abstract:Feline gastrointestinal eosinophilic sclerosing fibroplasia was diagnosed in an 8-month-old Scottish fold that had a primary gastrointestinal mass involving the stomach, duodenum and mesenteric lymph nodes. Histopathologically, the most characteristic feature of this mass was granulation tissue with eosinophil infiltration and hyperplasia of sclerosing collagen fiber. Immunohistochemically, large spindle-shaped cells were positive for smooth muscle actin and vimentin. This case emphasizes the importance of feline gastrointestinal eosinophilic sclerosing fibroplasia as a differential diagnosis of gastrointestinal neoplastic lesions such as osteosarcoma and mast cell tumor in cats.
Keywords:cat  gastrointestinal tract  granulation tissue  eosinophil  fibrosis
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