Strobilocercus fasciolaris infection with hepatic sarcoma and gastroenteropathy in a Wistar colony |
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| Authors: | Mahesh Kumar J Reddy P L Aparna V Srinivas G Nagarajan P Venkatesan R Sreekumar C Sesikaran B |
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| Institution: | Animal House, Centre For Cellular and Molecular Biology, Uppal Road, Hyderabad 500 007, India. mahesh73@ccmb.res.in |
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| Abstract: | Tapeworm cysts were identified in liver of Wistar rats and it induced fibrosarcoma in liver and gastroenteropathy in stomach and intestine. The tapeworm larva was confirmed as Strobilocercus fasciolaris by PCR linked mitochondrial DNA sequencing. Light microscopy, special staining (masson trichrome) and immunoflouresence supported the diagnosis of fibrosarcoma. Infiltration of plasma cells, macrophages and eosinophils were observed in the liver section. Gastric mucosal hyperplasia, dilation of gastric glands with secretion, intestinal mucosal cell hyperplasia, proliferation of duodenal submucosal glands were confirmed by light microscopy and supported by PAS, AB staining. The concomitant development of hepatic sarcoma and gastroenteropathy by larvae of Taenia taeniaeformis (S. fasciolaris) infection is very rare and is the first reported case in Wistar rats to our knowledge. |
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