Bioactive phenolics and terpenoids from Manglietia insignis |
| |
| Institution: | 1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, Yunnan, People''s Republic of China;2. Shanghai Key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, People''s Republic of China;3. University of Chinese Academy of Sciences, Beijing 100049, People''s Republic of China;1. School of Life Sciences, Northwest University, 229 Taibai Bei Road, Xi''an 710069, China;2. School of Life Sciences, Luoyang Normal University, 6 Jiqing Road, Luoyang 471934, China;1. Plant Science Institute, School of Life Science, Yunnan University, Kunming 650091, Yunnan Province, China;2. Ecology Institute, School of Life Science, Yunnan University, Kunming 650091, Yunnan Province, China;3. Dali Branch of Yunnan Tobacco Company, Dali 671000, Yunnan Province, China;1. Key Laboratory of South China Agricultural Plant Genetics and Breeding, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou 510650, PR China;2. Key Laboratory of Plant Resources Conservation and Sustainable Utilization, South China Botanical Garden, the Chinese Academy of Sciences, Guangzhou, 510650, PR China;3. P. O. Box 7, Miki-cho post office, Ikenobe 3011-2, Takamatsu 761-0799, Kagawa-ken, Japan;1. Department of Anatomical Pathology, St Vincent''s Hospital, University of Melbourne, Fitzroy, Australia;2. Department of Pathology, Peter MacCallum Cancer Centre, East Melbourne, Australia;3. Department of Haematology and Medical Oncology, Peter MacCallum Cancer Centre, University of Melbourne, East Melbourne, Australia;4. Department of Surgery, St Vincent''s Hospital, University of Melbourne, Fitzroy, Australia;5. Department of Surgery, Austin Health, University of Melbourne, Heidelberg, Australia;6. Department of Respiratory and Sleep Medicine, St Vincent''s Hospital, University of Melbourne, Fitzroy, Vic, Australia;1. Laboratory of Mucosal Exposome and Biomodulation, Department of Biomedical Sciences, Medical Research Institute, Pusan National University School of Medicine, Yangsan, 50612, South Korea;2. Immunoregulatory Therapeutics Group in Brain Busan 21 Project, Busan, 46241, South Korea |
| |
| Abstract: | Four new compounds, maninsigins A–D (1–4), including two new neolignans (1–2) and two new sesquiterpenes (3–4), as well as ten known compounds (5–14), were isolated from the leaves and stems of Manglietia insignis. Their structures were established on the basis of extensive spectroscopic analyses. In addition, some compounds were tested for their cytotoxic and neurite outgrowth-promoting activities, as well as their antagonistic activity toward FXR ligand. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
