| 基因A型和C型鸭甲型肝炎病毒卵黄抗体的研制及应用 |
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| 引用本文： | 王继练,张焕容,王栋.基因A型和C型鸭甲型肝炎病毒卵黄抗体的研制及应用[J].动物医学进展,2016(9). |
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| 作者姓名： | 王继练 张焕容 王栋 |
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| 作者单位： | 西南民族大学生命科学与技术学院,四川成都,610041 |
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| 基金项目： | 中央高校基本科研业务费专项资金项目(2014NZYQN58)；兽医专业学位研究生教育实践基地建设项目 |
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| 摘 要： | 旨在研制基因A型和C型鸭甲型肝炎病毒(DHAV)单价及二价高免卵黄抗体,以满足实际生产中基因A型和C型DHAV单独或混合感染防控的需要。采用基因A型和C型DHAV强毒株作为抗原制备单价和二价油乳剂灭活疫苗免疫接种高产蛋鸡,制备了高效价的基因A型和C型DHAV单价及二价高免卵黄抗体,卵黄抗体鸭胚中和效价在1∶204与1∶281之间,单价及二价卵黄抗体防治试验证明,所制备的卵黄抗体防治效果良好。
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| 关 键 词： | 鸭甲型肝炎病毒 基因型 卵黄抗体 防治 |
Development and Application of Egg Yolk Antibodies Against Hepatitis A Virus Genotypes A and C |
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| Abstract: | The objective of this study was to develop monovalent and bivalent egg yolk antibodies against duck hepatitis A virus genotypes A and C to meet the requirement of prevention and treatment of duck viral hepatitis caused by duck hepatitis A virus genotypes A and C.Firstly,virulent duck hepatitis A virus geno-type A and C strains were used as antigens to prepare monovalent and bivalent duck hepatitis A virus geno-type A and C inactivated vaccine in oil-emulsion with Freud's adjuvant.Then the vaccines were used to im-munize layer hens to produce immunized eggs for preparing highly immunized egg yolk antibodies.The good experimental prevention and treatment effects were acquired with both monovalent and bivalent egg yolk antibodies. |
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| Keywords: | Duck hepatitis A virus genotype egg yolk antibody prevention and treatment |
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