| PHA复方制剂对鸡新城疫疫苗的免疫增强作用 |
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| 引用本文： | 刘艳艳,秦光,李继昌.PHA复方制剂对鸡新城疫疫苗的免疫增强作用[J].东北农业大学学报,2012,43(6):32-35. |
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| 作者姓名： | 刘艳艳 秦光 李继昌 |
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| 作者单位： | 东北农业大学动物医学学院,哈尔滨,150030 |
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| 基金项目： | 黑龙江省教育厅振兴东北老工业基地建设重大项目 |
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| 摘 要： | PHA复方制剂由植物血凝素(PHA)为主药组成,为探讨其对鸡新城疫(ND)疫苗的免疫增强作用,将复方制剂按体重0.05、0.2和0.3 g.kg-1三个剂量灌服,对Lasota疫苗免疫鸡ND的抗体效价、免疫球蛋白、血液中T淋巴细胞进行检测,攻毒后计算攻毒保护率。结果表明,PHA复方制剂0.05、0.2 g.kg-1组可显著提高抗体、IgG和IgA(P<0.05),提高血中T淋巴细胞数(P<0.05)和攻毒保护率,显示PHA复方制剂对ND疫苗有免疫增强作用及免疫保护作用。
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| 关 键 词： | PHA复方制剂 鸡 新城疫 免疫增强 保护作用 |
Study on immunity enhancement of ND vaccine under PHA compound preparation in chicken |
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| LIU Yanyan
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QIN Guang
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LI Jichang.Study on immunity enhancement of ND vaccine under PHA compound preparation in chicken[J].Journal of Northeast Agricultural University,2012,43(6):32-35. |
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| Authors: | LIU Yanyan QIN Guang LI Jichang |
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| Institution: | (School of Veterinary Medicines,Northeast Agricultural University,Harbin 150030,China) |
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| Abstract: | The pharmacodynamics experiment of immunity enhancement to ND about the preparation to be explored,the compound preparation were gavaged at doses of 0.05,0.2,0.3 g·kg-1 which were composed with PHA,the antibody titer,immune globulin and blood T lymphocyte number were detected to chicken in different days.The results showed that the compound preparation could significant improve the serum antibodies level and the concentration of IgG,IgA(P<0.05),and it could increase blood T lymphocyte number and have good protection to the virus infection(P<0.05).It suggested the compound preparation had immunity enhancement function to ND vaccine and had enhancement function of immune protection. |
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| Keywords: | PHA compound chicken ND immune protection |
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