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Olfactory neuroblastoma in a horse
Authors:Yamate Jyoji  Izawa Takeshi  Ogata Keiko  Kobayashi Osamu  Okajima Ryoko  Kuwamura Mitsuru  Kotani Takao  Aoki Mika
Institution:Department of Veterinary Pathology, Life and Environmental Sciences, Osaka Prefecture University, Osaka, Japan.
Abstract:An 11-year-old thoroughbred gelding was euthanatized because of right nasal cavity tumor. The tumor consisted of round to oval cells with a scanty cytoplasm and hyperchromatic nuclei. Homer-Wright rosettes and pseudorosettes, as well as microcysts were seen. Neoplastic cells were immunoreactive to vimentin, S-100 protein, and neuron-specific enolase, glial fibrillary acidic protein and microtube-associated protein in varying degrees, indicating neurogenic nature. Based on these findings, this tumor was diagnosed as an olfactory neuroblastoma. Since this type is an uncommon tumor showing histological variety, the nature is discussed.
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