华钩藤中非生物碱类成分的研究 |
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引用本文: | 陈霞,;张楠,;刘建华,;张援虎.华钩藤中非生物碱类成分的研究[J].贵州大学学报(农业与生物科学版),2014(3):91-94. |
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作者姓名: | 陈霞 ;张楠 ;刘建华 ;张援虎 |
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作者单位: | [1]贵州大学药学院,贵州贵阳550001; [2]贵州省中国科学院天然产物化学重点实验室,贵州贵阳550002 |
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基金项目: | 科技部973计划前期研究专项项目(2012CB722601) |
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摘 要: | 本文对华钩藤95%乙醇提取物的氯仿部分的非生物碱类成分进行分离纯化,通过理化性质和波谱技术(MS、1H-NMR、13C-NMR)鉴定所得化合物的结构。分离得到8个非生物碱类成分,分别为乌苏酸(I)、β-谷甾醇(II)、奎洛维酸(III)、胡萝卜苷(IV)、奎洛维酸-3-O-β-D-海藻糖苷(V)、3β,5α,6β-三羟基豆甾烷(Ⅵ)、齐墩果酸(VII),奎洛维酸-3-O-β-D-吡喃葡萄糖苷(28→1)-β-D-吡喃葡萄糖苷(VIII),其中化合物III、V、Ⅵ、VIII为首次从钩藤属植物中分离得到。
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关 键 词: | 华钩藤 非生物碱 波谱解析 |
The Non -alkaloid Constituents of Uncaria sinensis (Oliv.) Havil |
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Institution: | CHEN Xia , ZHANG Nan, LIU Jian-hua , ZHANG Yuan-hu ( 1. College of Pharmacy, Guizhou Univer- sity, Guiyang Guizhou 550001, China; 2. The Key Laboratory of Chemistry for Natural Products of Guizhou Province and Chinese Academy of Sciences, Guiyang Guizhou 550025, China) |
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Abstract: | The non- alkaloid constituents were separated and purified from the chloroform portion of 95% ethylalcohol extract in Uncaria sinensis ( Oliv. ) Havil, and the structures were identified by physical characteristics and spectral analysis ( MS, 1 H - NMR, 13 C - NMR ). Eight non - alkaloid compounds were isolated and identified as ursolic acid ( I ),β - sitosterol ( II ), quinovic acid (III ), daucosterol ( IV ), quinovic acid - 3 - O - β - D - fucopyranoside ( V), 3, 5, 6 - trihydroxy - phytosteranes ( VI), oleanolic acid ( VII), quinovic acid - 3 - O - β - D - glucopyranoide ( 28→1 ) - β - D - glucopyranoside ( VIII), and compounds III, V, VI, VIII were isolated from this genus for the first time. |
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Keywords: | Uncaria sinensis Non - alkaloids Spectral analysis |
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