| 犬接种狂犬病疫苗后白细胞介素2和γ干扰素的浓度检测 |
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| 引用本文： | 孙泉云,顾永远,薛霞,李凯航,鞠龚讷.犬接种狂犬病疫苗后白细胞介素2和γ干扰素的浓度检测[J].北京农业,2007(21):53-55. |
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| 作者姓名： | 孙泉云 顾永远 薛霞 李凯航 鞠龚讷 |
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| 作者单位： | 1. 上海市畜牧兽医站,上海,201103
2. 上海市闵行区动物疾病预防控制中心,上海,201109 |
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| 基金项目： | 上海市重大动物疫病检测专项 |
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| 摘 要： | 2005年对狂犬病活疫苗免疫的犬只进行了细胞免疫性能的评估,采用ELISA检测免疫犬和非免疫对照犬的血清中白细胞介素2和γ干扰素的浓度。结果免疫犬血清样品的IL-2和IFN-γ浓度分别于免疫后7d上升,至免疫后30d达到峰值,以后逐步下降,但至120d仍保持较高浓度。未免疫狂犬病疫苗的对照组犬,血清中IL-2和IFN-γ浓度无明显变化。
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| 关 键 词： | 犬 ELISA 白细胞介素2 γ干扰素 血清浓度 检测 |
| 修稿时间： | 2007年6月7日 |
Detection of Serun Concentration of Interleukin2 and Interferon-gamma in Dogs after Immunisation with Rabies Vaccine |
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| Sun Quanyun,Gu Yongyuan,Xue Xia,Li Kaihang,Ju Gongne.Detection of Serun Concentration of Interleukin2 and Interferon-gamma in Dogs after Immunisation with Rabies Vaccine[J].Beijing Agriculture,2007(21):53-55. |
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| Authors: | Sun Quanyun Gu Yongyuan Xue Xia Li Kaihang Ju Gongne |
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| Institution: | Sun Quanyun Gu Yongyuan Xue Xia Li Kaihang Ju Gongne |
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| Abstract: | To evaluate the cellular immune response to rabies of the dogs vaccinated with rabies vaccine, blood samples of 24 dogs were assessment of the serum concentration of interleukin2 and interferon-gamma by ELISA.The results showed the serum concentration of IL-2 and IFN-γ were rised 7 days postvaccination, and reached a peak by 30 days postvaccination followed by a decline. The serum concentration of IL-2 and IFN-γ from unvaccinated control dogs were not stimulated by rabies vaccine. |
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| Keywords: | Dog ELISA Rabies vaccine Interleukin 2 Interferon-gamma Serum concentration Detection |
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