Treatment of periodontitis in dogs with tinidazole |
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| Authors: | E M Sarkiala |
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| Institution: | College of Veterinary Medicine, Department of Clinical Sciences, Hämeentie 57, 00580 Helsinki, Finland |
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| Abstract: | The efficacy of tinidazole administered in addition to a single course of scaling was evaluated in the treatment of periodontitis in 14 small dogs. Periodontal parameters, such as pocket depth, gingival bleeding after probing, furcation involvements and tooth mobility, were examined at baseline, 14 days, and three and six months. After thorough scaling and root planing, tinidazole (15 to 25 mg/ kg) or placebo was given orally twice daily for seven days. Tinidazole plus scaling resulted in a statistically significant decrease from the baseline values in the mean pocket depth, percentage of deep (greater than 3 mm) pockets and frequency of gingival bleeding for six months. In the placebo plus scaling group, mean pocket depth, percentage of deep pockets, frequency of gingival bleeding and number of furcation involvements were significantly lower at 14 days than at baseline. The decrease in bleeding tendency was significantly greater in the tinidazole than in the placebo group at the first two follow-up visits. Similarly, pocket depth and the percentage of deep pockets at the last two visits had decreased significantly more in the tinidazole group than in the placebo group. The use of tinidazole in addition to scaling seems to result in longer lasting improvement of the periodontal condition in dogs with periodontitis than scaling alone. |
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