| 人工感染猪附红细胞体病的病理组织学研究 |
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| 引用本文： | 尤立娜,巴彩凤,冯会权,李慧平,王凯,林小丰,廉长红,石蕾.人工感染猪附红细胞体病的病理组织学研究[J].中国畜牧兽医,2008,35(6). |
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| 作者姓名： | 尤立娜 巴彩凤 冯会权 李慧平 王凯 林小丰 廉长红 石蕾 |
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| 作者单位： | 辽宁医学院实验动物中心,锦州,121001 |
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| 基金项目： | 辽宁省科技计划
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| 摘 要： | 为观察昆明小鼠人工感染猪附红细胞体后的病理组织学变化。用常规病理学方法,对6只腹腔注射感染猪附红细胞体的小鼠进行病理解剖学和病理组织学研究,光镜下观察并描述小鼠红细胞感染附红细胞体后的形态变化。剖检可见主要器官和皮下瘀血,胸腹部皮下脂肪黄染,病理组织学变化的主要特征是心、肝、脾、肺、肾等主要脏器实质细胞变性、坏死,毛细血管扩张充血、出血,脾窦内含铁血黄素沉着。结果表明,猪附红细胞体感染小鼠模型的成功建立,镜下红细胞的形态特征及主要器官剖检和病理组织学变化与文献报道的猪附红细胞致病特征基本吻合,存在的差异可能与不同地域猪附红细胞体病原株致病性有关。
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| 关 键 词： | 小鼠 猪附红细胞体 病理解剖学 病理组织学 |
Pathohistology of Experimental Mouse Model with Mycoplasma Suis |
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| YOU Lina,BA Cai-feng,FENG Hui-quan,LI Hui-ping,WANG Kai,LIN Xiao-feng,LIAN Chang-hong,SHI Lei.Pathohistology of Experimental Mouse Model with Mycoplasma Suis[J].China Animal Husbandry & Veterinary Medicine,2008,35(6). |
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| Authors: | YOU Lina BA Cai-feng FENG Hui-quan LI Hui-ping WANG Kai LIN Xiao-feng LIAN Chang-hong SHI Lei |
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| Abstract: | To observe the pathohistology of a Kunming mouse infected with mycoplasma suis.Mice were inoculated with mycoplasma suis through peritoneal injection,with routine pathobiology method,pathological anatomy and pathologic histology were performed,light microscope was used to observe the infected red blood cells at first,which help to describe the shape of mycoplasma suis infected red blood cells.The inspection of anatomy shows the major organs and subcutaneouly have congestion,stained yellow of subcutaneous fat was observed in thoracic part and abdominal region.The pathologic histology of heart,liver,spleen,lung,kidney is characterisied by parenchyma cell degeneration and necrosis,including angiotelectasis congestion and haemorrhagia,hemosiderin pigmentation was inspected in sinus lienis.The model of infection with mycoplasma suis was established in mice,the results of pathohistology and morphologic characteristics of red blood cells were identical to the documents.The discrepancy is probably concerned with different agent strains. |
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| Keywords: | mouse mycoplasma suis anatomopathology pathohistology |
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