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Effects of Antimicrobial Peptide on Growth Performance and Immune Function of 817 Broiler Hybrids
Authors:WANG Li  CHEN Xiao  WANG Shu-quan
Institution:1. College of Science and Technology, Nanchang University, Nanchang 330029, China; 2. College of Animal Husbandry and Veterinary, Jinzhou Medical University, Jinzhou 121001, China
Abstract:This experiment was conducted to investigate the effects of antimicrobial peptide on growth performance and immune function of 817 broiler hybrids. Nine hundred one-day-old 817 broiler hybrids were chosen and randomly divided into 5 groups with 6 replicates per group and 30 broilers per replicate.The broilers in control group were fed with basal diet, broilers in the antibiotic group were fed with basal diet supplemented 150 mg/kg aureomycin,and that in groups Ⅰ,Ⅱ and Ⅲ were fed with basal diet supplemented 100,200 and 300 mg/kg antimicrobial peptide,respectively. The experiment period was 42 days. The results showed that average daily gain of 817 broiler hybrids in groups Ⅱ and Ⅲ was significantly increased (P<0.05),meanwhile the F/G was significantly decreased at 1-21 days old (P<0.05).The immune organ indexes of thymus,bursa of Fabricius and spleen were significantly increased at 21 and 42 days old (P<0.05),and the antibody level against ND and T lymphocyte transformation rate of 42 days old 817 broiler hybrids were improved (P<0.05). It indicated that antimicrobial peptide could increased growth performance and immune function of 817 broiler hybrids as same with aureomycin,and appropriate dosage of antimicrobial peptide was 200 mg/kg in this experiment.
Keywords:817 broiler hybrids  antimicrobial peptide  growth performance  immunity function  
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