Efficacy and safety of 3 versus 5 days of meloxicam as an analgesic for feline onychectomy and sterilization |
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| Authors: | Ingwersen Walt Fox Ronald Cunningham Gail Winhall Martha |
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| Institution: | Boehringer Ingelheim Canada Ltd, Vetmedica Division, 5180 South Service Road, Burlington, Ontario L7L 5H4 (Ingwersen, Cunningham, Winhall); Bay Cities Animal Hospital, 3001 New Street, Burlington, Ontario L7R 1K3 (Fox). |
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| Abstract: | Three- or 5-day courses of meloxicam 0.2 mg/kg body weight (BW) subcutaneously pre- or postoperatively on Day 1 followed by 0.05 mg/kg BW, PO per day thereafter] were assessed for analgesic efficacy and safety in 50 client-owned cats undergoing onychectomy and sterilization. Primary outcome parameters were analgesia score, gait/lameness score, and need for rescue analgesia assessed at times 0, 1, 4, 7, 24, 28, 35, 48, 52, 57 hours and on Day 5. Packed cell volume/total solids and serum biochemistry were assessed at time 0 and Days 3 and 5. There were no differences in efficacy and safety parameters regardless of the treatment protocol employed and no cat required rescue analgesia. The patients that received meloxicam preoperatively had statistically better gait/lameness scores than those that received meloxicam postoperatively, supporting the principle of preemptive analgesia. |
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