Anti-inflammatory activity of the hydrosoluble fraction of Euphorbia royleana latex |
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| Authors: | Bani S Kaul A Jaggi B S Suri K A Suri O P Sharma O P |
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| Institution: | Department of Pharmacology, Regional Research Laboratory, Canal Road, Jammu, India. |
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| Abstract: | The hydrosoluble fraction of Euphorbia royleana latex (AER), administered by gavage at doses of 50-200 mg/kg, showed dose-dependent anti-inflammatory and anti-arthritic effects in different acute and chronic test models in rats and mice. It reduced the exudate volume and the migration of leukocytes and showed a poor inhibitory effect on the granuloma formation induced by cotton pellets, while it had a low ulcerogenic score. The oral LD(50) was more than 1500 mg/kg in both rats and mice. |
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| Keywords: | Euphorbia royleana Anti-inflammatory activity Anti-arthritic activity |
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