The effect of dietary lysine deficiency on the immune response to Newcastle disease vaccination in chickens |
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| Authors: | Chen C Sander J E Dale N M |
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| Institution: | Department of Poultry Science, College of Agriculture, The University of Georgia, Athens, GA 30602, USA. |
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| Abstract: | The effect of lysine deficiency on chicken immune function was evaluated using broiler chickens fed a diet with lysine at 67% of the control diet (1.24% lysine). The evaluation of humoral immune function was conducted by measuring the antibody production to a live Newcastle disease virus (NDV) vaccination using the hemagglutination inhibition (HI) test and enzyme-linked immunosorbent assay (ELISA). The cellular immune function was evaluated through the use of cutaneous basophil hypersensitivity test. The antibody response to NDV vaccination was reduced in broiler chickens fed a lysine-deficient diet when measured by ELISA but not when measured by HI. The cell-mediated immune response was also reduced by lysine deficiency. |
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