Research Progress of Copy Number Variation in Poultry Breeding |
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| Authors: | ZHANG Yi BAI Hao BI Yulin LU Ao HUANG Yanli CHEN Guohong CHANG Guobin |
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| Institution: | 1. College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China;2. Joint International Research Laboratory of Agriculture and Agri-Product Safety of Ministry of Education of China, Institute of Agricultural Science and Technology Development, Yangzhou University, Yangzhou 225009, China;3. College of Innovation and Entrepreneurship, Yangzhou University, Yangzhou 225009, China |
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| Abstract: | Copy number variation (CNV) is an important type of genetic variation which widely exists in livestock and poultry genomes. It usually occurs in the form of deletion or duplication of large DNA sequences, which directly affects gene expression and function. CNV is closely related to many genetic diseases and phenotypic traits, and therefore has attracted close attention of animal genetics and breeding workers. The formation causes, action mechanism, detection methods, and the research progress of CNV in poultry were summarized in this article, and the difficulties and problems in current CNV studies were discussed, which aims to provide a reference for the realization of CNV as a molecular genetic marker in poultry for assisted breeding. |
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| Keywords: | copy number variation genome poultry breeding |
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