| H5N2亚型禽流感病毒中药佐剂灭活苗对公雏鸡外周血T淋巴细胞亚群的影响 |
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| 引用本文： | 马德慧,薛江东,姚春雨,孟宪龙,杨明霞,刘国文.H5N2亚型禽流感病毒中药佐剂灭活苗对公雏鸡外周血T淋巴细胞亚群的影响[J].中国畜牧兽医,2009,36(9):131-133. |
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| 作者姓名： | 马德慧 薛江东 姚春雨 孟宪龙 杨明霞 刘国文 |
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| 作者单位： | （1.内蒙古民族大学动物科技学院， 通辽 028000； 2.吉林大学畜牧兽医学院， 长春 130062；3.金宇保灵生物药品有限公司， 呼和浩特 010030） |
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| 基金项目： | 国家科学基金资助项目 |
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| 摘 要： | 将200只海兰褐公雏鸡分为4组，每组50只。A组注射H5N2亚型禽流感病毒黄芪多糖油乳剂灭活苗；B组注射H5N2亚型禽流感病毒人参皂苷油乳剂灭活苗；C组注射H5N2亚型禽流感病毒普通油乳剂灭活苗；D组注射生理盐水油乳剂（空白对照）。分别在免疫前随机选取5只鸡心脏采血，EDTA抗凝。于免疫后5、12、19 d每组每次分别随机选取5只鸡心脏采血，EDTA抗凝，检查各阶段各组鸡外周血T淋巴细胞亚群变化情况。结果表明，免疫后第12天，黄芪多糖和人参皂苷可提高CD4+/CD8+淋巴细胞的比值，与普通疫苗和对照组相比，差异极显著（P<0.01）；黄芪多糖和人参皂苷可提高CD4+淋巴细胞亚群的百分率，与免疫前相比，差异极显著或显著（P<0.01或P<0.05）。
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| 关 键 词： | 禽流感灭活苗 黄芪多糖 人参皂苷 T淋巴细胞亚群 |
Effect of Inactivated Chinese Herbs Adjuvant Vaccines against H5N2 Subtype AIV on Peripheral Blood T Lymphocyte Subgroup in Chickling |
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| MA De-hui,XUE Jiang-dong,YAO Chun-yu,MENG Xian-long,YANG Ming-xia,LIU Guo-wen.Effect of Inactivated Chinese Herbs Adjuvant Vaccines against H5N2 Subtype AIV on Peripheral Blood T Lymphocyte Subgroup in Chickling[J].China Animal Husbandry & Veterinary Medicine,2009,36(9):131-133. |
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| Authors: | MA De-hui XUE Jiang-dong YAO Chun-yu MENG Xian-long YANG Ming-xia LIU Guo-wen |
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| Institution: | (1.Animal Science and Technology College, Inner Mongoia University for Nationality, Tongliao 028000, China; 2.College of Animal Science and Veterinary Medicine, Jilin University, Changchun 130062, China; 3.Jinyu Baoling Bio-pharmaceuticals Ltd, Hohhot 010030, China) |
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| Abstract: | 200 male Hyline Brown chicklings were divided into 4 groups(A,B,C and D),each group with 50 broilers.The group A was injected with inactivated oil-emulsion vaccines against H5N2 subtype avian influenza virus with adjuvant of astragalus polysaccharides(APS),the group B was injected with inactivated oil-emulsion vaccines against H5N2 subtype avian influenza virus with adjuvant of ginseng saponin(GS),the group C and D were injected with inactivated oil-emulsion vaccines against H5N2 subtype avian influenza vir... |
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| Keywords: | avian influenza virus inactivated vaccines astragalus polysaccharides ginseng saponin T lymphocyte subgroup |
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