| 雏鸡感染柔嫩艾美耳球虫后脂质过氧化物的变化 |
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| 引用本文： | 郑明学,韩克光,古少鹏,高建光,史喜菊.雏鸡感染柔嫩艾美耳球虫后脂质过氧化物的变化[J].中国兽医学报,2002,22(3):236-237. |
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| 作者姓名： | 郑明学 韩克光 古少鹏 高建光 史喜菊 |
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| 作者单位： | 山西农业大学动物科技学院,山西,太谷,030801 |
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| 基金项目： | 山西省青年基金项目 ( 9710 32) |
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| 摘 要： | 为了探讨柔嫩艾美耳球虫 (E.tenella)对感染雏鸡的损伤机制 ,本试验给 10日龄海兰白公雏鸡口服柔嫩艾美耳球虫孢子化卵囊 8× 10 4个 /只 ,在感染后 2、4、6、7、9、12、16和 2 1d分别各取 5只雏鸡剖检 ,取盲肠并采血 ,观察盲肠病理组织学变化 ,测定盲肠组织及血清中的丙二醛 (MDA )、超氧化物歧化酶 (SOD)、谷胱甘肽过氧化物酶 (GSH- Px)的水平。结果表明 ,雏鸡在感染 E.tenella后 2～ 4d,盲肠开始出现损伤 ,同时 SOD和 GSH- Px活性也开始下降 ;感染后 4～ 7d,盲肠粘膜上皮和肠腺上皮细胞大量变性、坏死崩解 ,发生严重损伤时 ,盲肠及血清中 MDA含量显著增加 ,并持续到 9d,同时 SOD和 GSH- Px活性也显著下降 ;感染 9d后 ,损伤的盲肠组织及 MDA、SOD和 GSH- Px水平逐渐恢复 ,至 2 1d基本达到正常
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| 关 键 词： | 柔嫩艾美耳球虫 脂质过氧化物 雏鸡 |
| 文章编号： | 1005-4545(2002)03-0236-02 |
| 修稿时间： | 2001年10月18 |
Change of Lipid Peroxides in the Chickens Infected with Eimeria tenella |
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| ZHENG Ming-xue,HAN Ke-guang,GU Shao-peng,GAO Jian-guang,SHI Xi-ju.Change of Lipid Peroxides in the Chickens Infected with Eimeria tenella[J].Chinese Journal of Veterinary Science,2002,22(3):236-237. |
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| Authors: | ZHENG Ming-xue HAN Ke-guang GU Shao-peng GAO Jian-guang SHI Xi-ju |
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| Abstract: | To further probe into the mechanism of damnification in chicken coccidiosis, 10-day chickens were inoculated with sporulated oocysts of Eimeria tenella. Pathological changes in caeca and level of MDA?SOD?GSH-Px were respectively observed and determined 2,4,6,7,9,12,16,21 day post infection of E. tenella. The results showed: When caeca was barely injured, the activity of SOD and GSH-Px began to descend. The content of MDA increased significantly on the 4 th-7 th day postinoculation with a great deal of epithelia in caecal mucosa and gland to be in degeneration, necrosis and collapse and continued to the 9 th day. Meanwhile the activity of SOD and GSH-Px descended significantly. After the 9th postinoculation, injured caecal and the level of MDA?SOD?GSH-Px gradually began to come back. They basically came back on the 21 st day after inoculation. |
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| Keywords: | Eimeria tenella lipid peroxide chicken |
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