| 微生物源农药申嗪霉素的研制与应用 |
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| 引用本文： | 方运玲,孙爽,申阅,何亚文.微生物源农药申嗪霉素的研制与应用[J].农药学学报,2014,16(4):387-393. |
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| 作者姓名： | 方运玲 孙爽 申阅 何亚文 |
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| 作者单位： | 1.上海交通大学 生命科学技术学院, 微生物代谢国家重点实验室, 上海 200240 |
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| 摘 要： | 申嗪霉素是中国自主研发的一种新型微生物源农药,具有高效、安全、广谱等特点,其主要成分是甜瓜根际促生菌M18产生的次级代谢产物吩嗪-1-羧酸。文章重点就申嗪霉素产生菌M18的分离及其代谢产物的鉴定、申嗪霉素生物合成及调控机理最新研究进展、申嗪霉素高产工程菌株的构建和产业化、以及申嗪霉素大田防病试验结果及推广应用情况等进行详细综述,并对其抗菌作用机理进行探讨,旨在为申嗪霉素的生物合成机理研究、遗传和代谢改造以及推广应用提供参考。
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| 关 键 词： | 假单胞菌M18 微生物源农药 申嗪霉素 吩嗪-1-羧酸 |
| 收稿时间： | 2014/1/17 0:00:00 |
| 修稿时间： | 6/1/2014 12:00:00 AM |
Progress on the development and application of biopesticide Shenqinmycin |
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| FANG Yunling,SUN Shuang,SHEN Yue and HE Yawen.Progress on the development and application of biopesticide Shenqinmycin[J].Chinese Journal of Pesticide Science,2014,16(4):387-393. |
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| Authors: | FANG Yunling SUN Shuang SHEN Yue and HE Yawen |
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| Institution: | 1.State Key Laboratory of Microbial Metabolism, School of Life Sciences & Biotechnology, Shanghai Jiao Tong University, Shanghai 200240, China |
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| Abstract: | Shenqinmycin is a newly developed biopesticide containing the secondary metabolite phenazine-1-carboxylic acid (PCA) produced by Pseudomonas sp. M18. The discovery and characterization of Pseudomonas sp. M18 as well as the identification of metabolites were firstly introduced; The progress on Shenqinmycin biosynthetic mechanism and regulatory network was then summarized; The construction of high-yield engineered strain and industrialization of Shenqinmycin were further introduced; Finally, the application of Shenqinmycin in plant disease control and possible antifungal mechanisms of shenqinmycin were discussed. |
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| Keywords: | Pseudomonas sp M18 biopesticide Shenqinmycin phenazine-1-carboxylic acid |
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