Serum protein electrophoresis in spontaneous canine hyperadrenocorticalism |
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| Authors: | A H van den Broek J Lida |
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| Institution: | Department of Veterinary Clinical Studies, Royal (Dick) School of Veternary Studies, Summerhall, Edinburgh. |
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| Abstract: | The serum protein concentrations of dogs with confirmed spontaneous hyperadrenocorticalism were determined by agarose gel electrophoresis before and during treatment with mitotane. In untreated animals a significant increase was detected in the mean concentration of total protein and the mean concentration and percentage of alpha-2 globulin. The mean concentration and percentage of albumin and gamma-globulin were significantly decreased. In animals on treatment the mean concentration of total proteins and the mean concentration and percentage of beta-2 globulin were significantly reduced. |
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